Mestranol

Mestranol is a semisynthetic estrogen prodrug of ethynyl estradiol (Cay-10006486), an estrogen receptor agonist. It is demethylated in the liver to ethynyl estradiol. Mestranol has estrogenic properties, inducing RNA synthesis in homogenized mouse uteri following a dose of 1.6 µg/animal, which is 16-fold higher than the dose of ethynyl estradiol needed to induce a similar response. Formulations containing mestranol were previously used as oral contraceptives.Formal Name: 3-methoxy-19-norpregna-1,3,5(10)-trien-20-yn-17alpha-ol. CAS Number: 72-33-3. Synonyms: EE 3-ME, Ethynyl Estradiol 3-methyl ether, NSC 84032, SC-475, Delta-MVE. Molecular Formula: C21H26O2. Formula Weight: 310.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: Acetonitrile: 1 mg/ml, Ethanol: 1 mg/ml, Methanol: 1 mg/ml. SMILES: C[C@@]12[C@](CC[C@@]2(O)C#C)([H])[C@]3([H])CCC4=CC(OC)=CC=C4[C@@]3([H])CC1. InChi Code: InChI=1S/C21H26O2/c1-4-21(22)12-10-19-18-7-5-14-13-15(23-3)6-8-16(14)17(18)9-11-20(19,21)2/h1,6,8,13,17-19,22H,5,7,9-12H2,2-3H3/t17-,18-,19+,20+,21+/m1/s1. InChi Key: IMSSROKUHAOUJS-MJCUULBUSA-N.