217 products were found matching "K08551"!

1 mg/ml in 1X PBS, BSA free, sodium azide free. Estrogen receptor 2 Antibody targets Estrogen receptor 2, a nuclear hormone receptor encoded by the ESR2 gene and widely known as estrogen receptor beta or ER beta. Estrogen receptor 2 functions as a ligand-activated transcriptional regulator that mediates cellular...

1 mg/ml in 1X PBS, BSA free, sodium azide free. Estrogen receptor beta Antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 in the literature. ER beta functions as a ligand-activated transcriptional regulator that modulates cellular...

1 mg/ml in 1X PBS, BSA free, sodium azide free. ER beta antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 and ER beta in the literature. Estrogen receptor beta belongs to the steroid hormone receptor superfamily and functions as a...

0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. Estrogen receptor 2 Antibody targets Estrogen receptor 2, a nuclear hormone receptor encoded by the ESR2 gene and widely known as estrogen receptor beta or ER beta. Estrogen receptor 2 functions as a ligand-activated transcriptional regulator that mediates...

0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. ER beta antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 and ER beta in the literature. Estrogen receptor beta belongs to the steroid hormone receptor superfamily and...

0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. Estrogen receptor beta Antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 in the literature. ER beta functions as a ligand-activated transcriptional regulator that modulates...

Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...

(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...

Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...

Synthetic. Chemical. CAS: 10540-29-1. Formula: C26H29NO. MW: 371.51. Synthetic. Selective estrogen receptor modulator (SERM) used as adjuvant therapy for estrogen-dependent breast cancer. Antagonist of ER action in breast tissue and breast cancer cells and ER agonist in bone, uterus, and the cardiovasculature...

Erteberel is an estrogen receptor beta (ERbeta) agonist. It is selective for ERbeta over ERalpha in reporter assays using PC3 cells expressing the human receptors (EC50s = 0.66 and 19.4 nM, respectively). Ertebrel (5 µM) induces apoptosis and cell cycle arrest at the G2/M phase in U87MG and U251 glioblastoma cells....

Bazedoxifene (acetate) is a third generation selective estrogen receptor modulator (SERM). It is an indole-based ER ligand that binds to both ERalpha (IC50 = 26 nM) and ERbeta (IC50 = 99 nM). Bazedoxifene (actetate) antagonizes 17beta-estradiol-dependent MCF-7 and T47D breast cancer cell proliferation in vitro as...