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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
Cay70270-1 | 1 g | - |
6 - 10 business days* |
36.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and... more
Product information "Indomethacin"
Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively). It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes. Indomethacin reduces ocular inflammation induced by bovine serum in rabbits. It also reduces paw edema in a rat model of carrageenan-induced inflammation.Formal Name: 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid. CAS Number: 53-86-1. Molecular Formula: C19H16ClNO4. Formula Weight: 357.8. Purity: >99%. Formulation: (Request formulation change), A crystalline solid. Solubility: 0.1 M Na2CO3: 0.1 mg/ml (warming is required, DMF: >20.2 mg/ml, DMSO: >17.8 mg/ml, ETOH: >6.73 mg/ml, PBS (pH 7.2): <50 µg/ml. SMILES: CC1=C(CC(O)=O)C(C=C(OC)C=C2)=C2N1C(C3=CC=C(Cl)C=C3)=O. InChi Code: InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23). InChi Key: CGIGDMFJXJATDK-UHFFFAOYSA-N.
Keywords: | 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 70270 |
Properties
Application: | COX inhibitor |
MW: | 357.8 D |
Formula: | C19H16ClNO4 |
Purity: | >99% |
Format: | Crystalline Solid |
Database Information
CAS : | 53-86-1| Matching products |
KEGG ID : | K00509 | Matching products |
Handling & Safety
Storage: | +20°C |
Shipping: | +20°C (International: +20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H300, H317, H318, H335, H341, H360, H373, H413 |
P Phrases: | P201, P202, P260, P261, P264, P270, P271, P272, P273, P280, P312, P314, P321, P330, P301+P310, P302+P352, P304+P340, P305+P351+P338, P308+P313, P333+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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