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BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible inhibitor of chymotrypsin (Ki = 636 nM). Formal Name: 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one. CAS Number: 88070-98-8. Synonyms: BEL, Haloenol lactone, HELSS. Molecular Formula: C16H13BrO2. Formula Weight: 317.2. Purity: >95%. Formulation: A crystalline solid. Solubility: acidic PBS: <50 µg/ml, basic PBS: <50 µg/ml, DMF: 50 mg/ml, DMSO: 25 mg/ml, Ethanol: 5 mg/ml, PBS pH 7.2: <50 µg/ml. lambdamax: 224 nm. SMILES: Br/C=C1\CCC(C(=O)O\1)c1cccc2ccccc12. InChi Code: InChI=1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+. InChi Key: BYUCSFWXCMTYOI-ZRDIBKRKSA-N.