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Item number: Cay70700-5

BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible...

Keywords:	BEL, Haloenol lactone, HELSS, 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one
Application:	iPLA2 inhibitor
CAS	88070-98-8
MW:	317.2 D

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Bromoenol lactone

Item number: TGM-T14829-1mL

Description: Bromoenol lactone is a suicide-based irreversible, selective, potent inhibitor of calcium-independent phospholipase A2 (iPLA2beta, IC50: ~7 µM). It inhibits antigen-stimulated mast cell exocytosis without blocking Ca2+ influx. Target: Phospholipase. Smiles: Br\C=C1/CCC(C(=O)O1)c1cccc2ccccc12....

Keywords:	(6E)-Bromoenol lactone
CAS	88070-98-8
MW:	317.18 D

161.00€ *

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