Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Prostaglandin E2-d4 MaxSpec(R) Standard
Prostaglandin E2-d4 MaxSpec(R) Standard

Item number: Cay10007273-10

Prostaglandin E2-d4 (PGE2-d4) is intended for use as an internal standard for the quantification of PGE2 (Cay-14010) by GC- or LC-MS. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation,...
Keywords: Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Application: Standard
CAS 34210-10-1
MW: 356.5 D
169.00€ *
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N-(beta-ketocaproyl)-L-Homoserine lactone
N-(beta-ketocaproyl)-L-Homoserine lactone

Item number: Cay10011207-10

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Keywords: 3-O-C6-(L)-HSL, 3-oxo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-hexanamide
Application: Antibiotic
CAS 143537-62-6
MW: 213.2 D
From 51.00€ *
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Fingolimod
Fingolimod

Item number: Cay11975-5

Fingolimod is an immune modulator, a prodrug form of the sphingosine-1-phosphate (S1P) receptor agonist FTY720 phosphate (Cay-10008639), and a derivative of myriocin (Cay-63150). It selectively inhibits calcium-dependent cytosolic phospholipase A2 (cPLA2) over calcium-independent PLA2 (iPLA2) and secretory PLA2...
Keywords: 2-amino-2-[2-(4-octylphenyl)ethyl]-1,3-propanediol
Application: S1P receptor agonist
CAS 162359-55-9
MW: 307.5 D
From 87.00€ *
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11(S)-HETE
11(S)-HETE

Item number: Cay34510-25

11(S)-HETE is an oxylipin and the (S) enantiomer of 11(R)-HETE (Cay-34505). It is formed non-enzymatically from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). Levels of 11(S)-HETE are higher than those of 11(R)-HETE in isolated human plasma and serum and in LPS-stimulated isolated human plasma. Serum...
Keywords: 11S-hydroxy-5Z,8Z,12E,14Z-eicosatetraenoic acid
Application: Bioactive lipid studies
CAS 54886-50-9
MW: 320.5 D
From 218.00€ *
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A1-Phytoprostane-I
A1-Phytoprostane-I

Item number: Cay9000593-100

A1-Phytoprostane-I is a cyclopentenone isoprostane produced by the action of reactive oxygen species on alpha-linolenic acid in plants. There are two A1-phytoprostanes, both having the single ketone group on the ring structure. This isoform results from cyclization between carbons 9 and 13 of linolenic acid, as...
Keywords: 16-A1-Phytoprostane, Phytoprostane A1, PPA1, 2-(3-hydroxy-1-penten-1-yl)-5-oxo-3-cyclopentene-1-octanoic acid
Application: Metabolic studies
CAS 1035557-09-5
MW: 308.4 D
From 183.00€ *
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Lignoceric Acid-d3
Lignoceric Acid-d3

Item number: Cay28084-5

Lignoceric acid-d3 is intended for use as an internal standard for the quantification of lignoceric acid (Cay-13353) by GC- or LC-MS. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides. The deficient peroxisomal oxidation of...
Keywords: C24:0-d3, tetracosanoic-24,24,24-d3 acid
Application: GC-MS, LC-MS, internal standard, quantification, saturated very-long-chain fatty acid
CAS 851073-55-7
MW: 371.7 D
606.00€ *
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N-cis-dodec-5(Z)-enoyl-L-Homoserine lactone
N-cis-dodec-5(Z)-enoyl-L-Homoserine lactone

Item number: Cay19505-5

An N-acyl homoserine lactone
Keywords: (Z)-N-[(3S)-2-Oxooxolan-3-yl]dodec-5-enamide, 5-cis-C12-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-5Z-dodecenamide
Application: N-acyl homoserine lactone, microbial metabolite
CAS 945495-73-8
MW: 281.4 D
From 70.00€ *
Review
Friedelin
Friedelin

Item number: Cay43506-5

A phytosterol with diverse biological activities, scavenges DPPH radicals in a cell-free assay (IC50 = 21.1 mM), toxic to mosquito larvae and adults (LC50s = 456.99 and 891.23 µg/ml, respectively), decreases the proliferation of P. falciparum (IC50 = 250.7 ng/ml), reduces serum levels of GDH, ALT, and Ldh and...
Keywords: (-)-Friedelin, Friedelanone, NSC 55141,...
Application: Bioactive phytosterol
CAS 559-74-0
MW: 426.73 D
From 51.00€ *
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cis-12-Octadecenoic Acid
cis-12-Octadecenoic Acid

Item number: Cay43580-5

A monounsaturated fatty acid
Keywords: 18:1(12Z), FA 18:1, 12Z-octadecenoic acid
Application: Monounsaturated fatty acid
CAS 13126-37-9
MW: 282.47 D
From 65.00€ *
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LipidLaunch(TM) T Cell LNP Screening Set
LipidLaunch(TM) T Cell LNP Screening Set

Item number: Cay43932-1

A screening set of ionizable cationic lipids for use in LNP formulations for T cell transfection, formulated at 10 mg/ml in ethanol, includes some of the most commonly cited ionizable lipids used in nucleic acid-cargo LNPs for transfection of activated T cells, LNPs containing these lipids have been used to...
Keywords: LipidLaunch(TM) T Cell Lipid Nanoparticle Screening Set
Application: Ionizable cationic lipids, LNP formulation, T cell transfection screening set
1,833.00€ *
Review
1,2-Dioleoyl-sn-glycero-3-PC (solution)
1,2-Dioleoyl-sn-glycero-3-PC (solution)

Item number: Cay43870-5

A phospholipid, has commonly been used alone, or with other components, in the generation of micelles, liposomes, and other types of artificial membranes, has also been used in combination with other lipids in the generation of LNPs for the delivery of mRNA and microRNA in vivo, intravenous administration of LNPs...
Keywords: 1,2-Dioleoyl-sn-glycero-3-Phosphocholine, DOPC, PDD 111, sn-3-Dioleoyllecithin,...
Application: Phospholipid
CAS 4235-95-4
MW: 786.13 D
From 62.00€ *
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alpha-Galactosylceramide
alpha-Galactosylceramide

Item number: AG-CN2-0013-C250

Immunostimulant [1, 2, 3]. Potent stimulator of natural killer T (NKT) cells [4, 5]. Specific ligand of the lipid-binding MHC class I-like protein CD1d in human and mouse NKT cells [5]. Protects against LPS-induced shock [7]. Potent antitumor compound [2, 6, 8].
Keywords: alpha-Gal-Cer, KRN7000
Application: Bioassays
MW: 858,3 D
From 121.00€ *
Review
39 from 346 pages