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Lauric Acid
Item number: Cay10006626-25
Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil. Lauric acid induces the activation of NF-kappaB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1alpha in RAW 264.7 cells when used at a concentration of 25 µM.Formal Name: dodecanoic...
| Keywords: | C12:0, Dodecanoic Acid, NSC 5026, dodecanoic acid |
| Application: | Lipid assays |
| CAS | 143-07-7 |
| MW: | 200.3 D |
From 23.00€
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(±)12(13)-EpOME-d4
Item number: Cay10009996-25
(±)12(13)-EpOME-d4 is intended for use as an internal standard for the quantification of 12(13)-EpOME by GC- or LC-MS. 12(13)-EpOME is an epoxide formed primarily via metabolism of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909) by the cytochrome P450 (CYP) isoforms CYP2J2, CYP2C8, and CYP2C9, however, CYP1A1 can...
| Keywords: | (±)-Vernolic Acid-d4, (±)12,13-EODE-d4, Isoleukotoxin-d4, (±)12(13)epoxy-9Z-octadecenoic-9,10,12,13-d4 acid |
| Application: | Standard |
| MW: | 300.5 D |
From 166.00€
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Lipoxin A5
Item number: Cay10011453-25
Lipoxin A5 (LXA5) is produced by enzymatic transformation of EPA by leukocytes. LXA5 slowly contracts pulmonary parenchymal strips from guinea pig with similar potency to that of LXA4 and LXB4. However, LXA5 does not exert the vasodilatory effects on aortic smooth muscle exhibited by LXA4 and LXB4.Formal Name:...
| Keywords: | LXA5, 5S,6R,15S-trihydroxy-7E,9E,11Z,13E,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 110657-98-2 |
| MW: | 350.5 D |
From 409.00€
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2-thio PAF
Item number: Cay60945-5
2-thio PAF is an isosteric analog of PAF. It is also a synthetic analog of PAF which contains an acetyl group attached by a thioester bond at the sn-2 position. It functions as a PAF receptor agonist, and its potency is comparable to PAF C-18 in rabbit platelet aggregation, and to PAF C-16 in the activation of...
| Keywords: | 1-O-hexadecyl-2-deoxy-2-thio-S-acetyl-sn-glyceryl-3-phosphorylcholine |
| Application: | Bioactive lipid assays |
| CAS | 96801-55-7 |
| MW: | 539.8 D |
From 295.00€
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O-Arachidonoyl Ethanolamine (hydrochloride)
Item number: Cay91050-1
Arachidonoyl ethanolamide (AEA) was the first endogenous cannabinoid to be isolated and characterized as an agonist acting on the same receptors (CB1 and CB2) as tetrahydrocannabinols (THC). Since that time, a number of related endocannabinoids have been isolated, most notably 2-arachidonoyl glycerol (2-AG)....
| Keywords: | Arachidonic Acid-(2-aminoethyl)-ester, O-AEA, Virodhamine, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-aminoethyl ester,... |
| Application: | CB1 receptor agonist, CB2 receptor agonist |
| CAS | 443129-35-9 |
| MW: | 384 D |
From 67.00€
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omega-3 Arachidonic Acid methyl ester
Item number: Cay10006454-1
omega-3 Fatty acids, represented primarily by docosahexaenoic acid, eicosapentaenoic acid, and alpha-linoleate, are essential dietary nutrients required for normal growth and development. omega-3 Arachidonic acid methyl ester is a neutral, lipid-soluble form of the rare fatty acid omega-3 arachidonic acid. The...
| Keywords: | 8Z,11Z,14Z,17Z-eicosatetraenoic acid, methyl ester |
| Application: | Bioactive lipid assays |
| CAS | 132712-70-0 |
| MW: | 318.5 D |
From 102.00€
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17(S)-HpDHA
Item number: Cay13185-25
17(S)-HpDHA is a mono-oxygenation product of docosahexaenoic acid in human whole blood, human leukocytes, human glial cells, and mouse brain. 17(S)-HpDHA is generally reduced to 17(S)-HDHA (Cay-10009799), a compound that serves as a precursor to 17(S)-resolvins. 17(S)-HDHA has been shown to inhibit TNF-alpha-induced...
| Keywords: | 17(S)-HpDoHE, 17(S)-hydroperoxy Docosahexaenoic Acid, 17S-hydroperoxy-4E,7Z,10Z,13Z,15Z,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 123673-33-6 |
| MW: | 360.5 D |
From 197.00€
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Resolvin D4
Item number: Cay13835-10
Resolvin D4 (RvD4) is a specialized pro-resolving mediator derived from docosahexaenoic acid (Cay-90310). It has been detected in human milk, in the dorsal pouch of mice before and after infection with S. aureus, and in untreated tissues from humans, mice, and sardines. RvD4, at 10 ng/mouse, reduces neutrophil...
| Keywords: | RvD4, (4S,5R,6E,8E,10Z,13Z,15E,17S,19Z)-4,5,17-trihydroxy-6,8,10,13,15,19-docosahexaenoic acid |
| CAS | 1025684-60-9 |
| MW: | 376.5 D |
From 228.00€
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I-BOP
Item number: Cay19600-100
I-BOP is a potent agonist of TP receptor-mediated platelet aggregation and vascular smooth muscle contraction. I-BOP induces human platelet aggregation with EC50 values of 0.34 nM and 0.174 nM at pH 7.4 and pH 6.0, respectively.Formal Name:...
| Keywords: | [1S-[1alpha,2alpha(Z),3beta(1E,3S*),4alpha]]-7-[3-[3-hydroxy-4-(4-iodophenoxy)-1-butenyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-... |
| Application: | TP receptor agonist |
| CAS | 128719-90-4 |
| MW: | 512.4 D |
From 126.00€
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9(S)-HpODE
Item number: Cay48410-50
9(S)-HpODE is produced by the action of arachidonate 5-LO on linoleic acid. It can be further metabolized by potato hydroperoxide dehydratase to colneleic acid.Formal Name: 9S-hydroperoxy-10E,12Z-octadecadienoic acid. CAS Number: 29774-12-7. Molecular Formula: C18H32O4. Formula Weight: 312.4. Purity: >98%....
| Keywords: | 9S-hydroperoxy-10E,12Z-octadecadienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 29774-12-7 |
| MW: | 312.4 D |
From 138.00€
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1,2-Dioleoyl-sn-glycerol
Item number: Cay62230-10
1,2-Dioleoyl-sn-glycerol is an analog of the protein kinase C-activating second messenger DAG. 1,2-Dioleoyl-sn-glycerol and 1,2-dioctanoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.Formal Name: 1,2-bis(O-9Z-octadecenoyl)-sn-glycerol. CAS Number: 24529-88-2. Molecular...
| Keywords: | 1,2-bis(O-9Z-octadecenoyl)-sn-glycerol |
| Application: | Bioactive lipid assays |
| CAS | 24529-88-2 |
| MW: | 621 D |
From 69.00€
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PtdIns-(4,5)-P2 (1,2-dioctanoyl) (sodium salt)
Item number: Cay64910-1
The phosphatidylinositol (PtdIns) represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns is phosphorylated to mono- (PtdIns-P, PIP), di- (PtdIns-P2, PIP2) and triphosphates (PtdIns-P3, PIP3). Hydrolysis of PIP2...
| Keywords: | DOPI-4,5-P2, Phosphatidylinositol-4,5-bisphosphate C-8, 1-(1,2R-dioctanoylphosphatidyl)inositol-4,5-bisphosphate,... |
| Application: | Bioactive lipid assays |
| MW: | 812.5 D |
From 87.00€
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