No results were found for the filter!
Prostaglandin F3alpha
Item number: Cay16990-50
Prostaglandin F3alpha (PGF3alpha) is a COX product of EPA. The biosynthesis of PGF3alpha from EPA was demonstrated in vitro in human and rabbit ocular tissues. It has only 25% affinity at the ovine luteal FP receptor compared to PGF2alpha.Formal Name: 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid....
| Keywords: | PGF3alpha, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid |
| Application: | Bioactive lipid assays |
| CAS | 745-64-2 |
| MW: | 352.5 D |
From 110.00€
*
(±)11(12)-EET-d11
Item number: Cay10006413-25
(±)11(12)-EET-d11 is intended for use as an internal standard for the quantification of 11(12)-EET by GC- or LC-MS. 11(R),12(S)-EET and 11(S),12(R)-EET are formed via epoxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) by a variety of cytochrome P450 (CYP) isoforms. 11(R),12(S)-EET is produced at...
| Keywords: | (±)11,12-EET-d11, (±)11(12)-epoxy-5Z,8Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20 acid |
| Application: | Standard |
| MW: | 331.5 D |
From 242.00€
*
(±)8(9)-EET-d11
Item number: Cay10009532-25
(±)8(9)-EET-d11 is intended for use as an internal standard for the quantification of (±)8(9)-EET (Cay-50351) by GC- or LC-MS. (±)8(9)-EET is a racemic mixture of the R/S enantiomeric forms biosynthesized from arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). (±)8(9)-EET is a major cytochrome P450 (CYP)...
| Keywords: | (±)8,9-EET-d11, (±)8,9-EpETrE-d11, (±)8(9)-epoxy-5Z,8Z,14Z-eicosatrienoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
| Application: | Standard |
| MW: | 331.5 D |
From 178.00€
*
(±)13-HDHA
Item number: Cay33500-25
(±)13-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. Fresh water hydra was shown to metabolize DHA to 13(R)-HDHA, presumably via the 11R-lipoxygenase activity. (±)13-HDHA is a potential marker of...
| Keywords: | (±)13-HDoHE, 13-hydroxy Docosahexaenoic Acid, (±)13-hydroxy-4Z,7Z,10Z,14E,16Z,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90780-53-3 |
| MW: | 344.5 D |
From 85.00€
*
Aspirin
Item number: Cay70260-50
Aspirin is a non-steroidal anti-inflammatory drug (NSAID) and a covalent inhibitor of COX-1 and COX-2 (IC50s = 4.45 and 13.88 µM, respectively, for the human enzymes). It is also an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS, IC50 = 750 µM for the ovine enzyme). Aspirin (6 µg/ml) inhibits...
| Keywords: | Acetylsalicylic Acid, NSC 27223, NSC 406186, 2-(acetyloxy)-benzoic acid |
| Application: | COX inhibitor |
| CAS | 50-78-2 |
| MW: | 180.2 D |
From 23.00€
*
trans-4,5-epoxy-2(E)-Decenal
Item number: Cay10004257-1
Polyunsaturated fatty acids such as arachidonate and linoeate, while essential to health maintenance, are subject to random peroxidation by ambient oxygen, resulting in fragmented and reactive decomposition products. One prominent autoxidation product of either trilinolein or arachidonic acid is...
| Keywords: | 3-(3-pentyloxiranyl)-2E-propenal, 3-[(2R,3R)-3-pentyloxiranyl]-2E-propenal |
| Application: | Bioactive lipid assays |
| CAS | 134454-31-2 |
| MW: | 168.2 D |
From 186.00€
*
5-PAHSA
Item number: Cay17043-5
5-PAHSA is a FAHFA in which palmitic acid is esterified at the 5th carbon of hydroxy stearic acid. PAHSA isoforms are the most abundant forms of FAHFA identified in the adipose tissue of glucose tolerant AG4OX mice. PAHSAs are synthesized in vivo in both mice and humans and are regulated by fasting and high-fat...
| Keywords: | 5-(palmitoyloxy)octadecanoic acid |
| Application: | Branched fatty acid ester of hydroxy fatty acid (FAHFA) |
| CAS | 1481636-41-2 |
| MW: | 538.9 D |
From 73.00€
*
4-Methylumbelliferyl 6-thio-Palmitate-beta-D-Glucopyranoside
Item number: Cay19524-1
4-Methylumbelliferyl 6-thio-palmitate-beta-D-glucopyranoside is a fluorogenic substrate of palmitoyl-protein thioesterase (PPT, also known as CLN1), a lysosomal hydrolase that removes long-chain fatty acyl groups from modified cysteine residues in proteins. 4-Methylumbelliferyl...
| Keywords: | Mu-6S-Palm-beta-Glc, 4-methyl-7-[[6-S-(1-oxohexadecyl)-6-thio-beta-D-glucopyranosyl]oxy]-2H-1-benzopyran-2-one |
| Application: | Fluorogenic palmitoyl-protein thioesterase substrate |
| CAS | 229644-17-1 |
| MW: | 592.8 D |
From 73.00€
*
Taurochenodeoxycholic Acid (sodium salt)
Item number: Cay20275-50
Taurochenodeoxycholic acid (TCDCA) is a taurine-conjugated form of the primary bile acid chenodeoxycholic acid (CDCA, Cay-10011286). Serum levels of TCDCA increase approximately 5-fold in within two hours and begin to decrease within four hours during an oral lipid tolerance test in humans. Serum levels of TCDCA are...
| Keywords: | NSC 681055, Taurochenodeoxycholate, TCDCA,... |
| CAS | 6009-98-9 |
| MW: | 521.7 D |
From 97.00€
*
5(Z),8(Z),11(Z)-Eicosatrienoic Acid
Item number: Cay90190-1
Eicosatrienoic acid accumulates in the tissues of animals fed diets deficient in both omega-3 and omega-6 fatty acids. It can be converted to 3-series cysteinyl-leukotrienes but cannot serve as a COX substrate. The kidneys from essential fatty acid deficient rats are less immunogenic when transplanted, and the...
| Keywords: | Mead Acid, 5Z,8Z,11Z-eicosatrienoic acid |
| Application: | Bioactive lipid assays |
| CAS | 20590-32-3 |
| MW: | 306.5 D |
From 122.00€
*
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA
Item number: Cay33479-100
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA (1-palmitoyl-d9 LPA) is intended for use as an internal standard for the quantification of 1-palmitoyl LPA (Cay-10010094, Cay-10010290) by GC- or LC-MS. 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid (Cay-10006627) at the sn-1 position. It induces reporter...
| Keywords: | 1-Palmitoyl-d9 LPA, hexadecanoic acid-13,13,14,14,15,15,16,16,16-d9, 2R-hydroxy-3-(phosphonooxy)propyl ester |
| Application: | GC-MS, LC-MS internal standard, quantification |
| CAS | 2830282-77-2 |
| MW: | 419.5 D |
From 102.00€
*
Lithocholic Acid
Item number: Cay20253-5
Lithocholic acid is a secondary bile acid that has been shown to cause cholestasis in animal models and has also been implicated in carcinogenesis. It is produced from chenodeoxycholic acid by bacterial action in the colon and can be conjugated with glycine or taurine. Whereas in normal colonic epithelium...
| Keywords: | 3alpha-hydroxy Cholanic Acid, LCA, Lithocholate, NSC 683770, (3alpha,5beta)-3-hydroxy-cholan-24-oic acid |
| Application: | Secondary bile acid |
| CAS | 434-13-9 |
| MW: | 376.6 D |
From 50.00€
*