1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA (1-palmitoyl-d9 LPA) is intended for use as an internal standard for the quantification of 1-palmitoyl LPA (Cay-10010094, Cay-10010290) by GC- or LC-MS. 1-Palmitoyl LPA is an analog of LPA that contains palmitic acid (Cay-10006627) at the sn-1 position. It induces reporter gene expression in PC12 cells expressing human lysophosphatidic acid receptor 4 (LPA4) when used at concentrations ranging from 0.01 to 10 µM. 1-Palmitoyl LPA (12-300 µM) induces aggregation of isolated human platelets, an effect that can be reversed by prostaglandin E1 (PGE1, Cay-13010), theophylline (Cay-23760), or EDTA. It also binds to calcium and magnesium and enhances the activity of ampicillin (Cay-14417), piperacillin (Cay-20766), and ceftazidime (Cay-14828) against P. aeruginosa isolates from patients with cystic fibrosis.Formal Name: hexadecanoic acid-13,13,14,14,15,15,16,16,16-d9, 2R-hydroxy-3-(phosphonooxy)propyl ester. CAS Number: 2830282-77-2. Synonyms: 1-Hexadecanoyl-d9-2-hydroxy-sn-glycero-3-phosphate, 16:0-d9 LPA, LPA 16:0-d9, PA(16:0-d9/0:0), 1-Palmitoyl-d9 LPA, 1-Palmitoyl-d9 Lysophosphatidic Acid. Molecular Formula: C19H30D9O7P. Formula Weight: 419.5. Purity: >99% deuterated forms (d1-d9). Formulation: (Request formulation change), A solution in chloroform. Solubility: Ethanol: 10 mg/ml. SMILES: O[C@@H](COP(O)(O)=O)COC(CCCCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O. InChi Code: InChI=1S/C19H39O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19(21)25-16-18(20)17-26-27(22,23)24/h18,20H,2-17H2,1H3,(H2,22,23,24)/t18-/m1/s1/i1D3,2D2,3D2,4D2. InChi Key: YNDYKPRNFWPPFU-QJVDOJJHSA-N.