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80-O16B
Item number: Cay37564-10
80-O16B is a disulfide bond-containing ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 for genome editing in mice. LNPs containing 80-O16B conjugated to phenylboronic acid (PBA) and encapsulating...
| Keywords: | N-[3-(dimethylamino)propyl]-N-[3-[2-(dodecyldithio)ethoxy]-3-oxopropyl]-beta-alanine, 2-(dodecyldithio)ethyl ester |
| Application: | Cationic lipidoid, LNP formation |
| CAS | 1624618-02-5 |
| MW: | 767.3 D |
From 178.00€
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Pentadecanoyl-L-carnitine (chloride)
Item number: Cay37677-10
Pentadecanoyl-L-carnitine is a cannabinoid (CB) receptor agonist (EC50s = 3.7 and 3.2 µM for CB1 and CB2 receptors, respectively, in a cAMP modulation assay). It is also an agonist at the serotonin (5-HT) receptor subtypes 5-HT1A and 5-HT1B (EC50s = 9.6 and 9.3 µM, respectively) and an antagonist at histamine H1 and...
| Keywords: | C15 Carnitine, L-Carnitine pentadecanoyl ester, L-Pentadecanoylcarnitine,... |
| Application: | CB receptor agonist |
| CAS | 173686-57-2 |
| MW: | 422 D |
From 84.00€
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1-Stearoyl-2-Eicosapentaenoyl-sn-glycero-3-PE
Item number: Cay37702-1
1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid (Cay-10011298) and eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908) at the sn-1 and sn-2 positions, respectively. It has been found in fish oils.Formal Name: 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid,...
| Keywords: | 18:0/20:5-PE, 1-Octadecanoyl-1-Eiocosapentaenoyl-sn-glycero-3-Phosphatidylethanolamine,... |
| Application: | Phospholipid |
| CAS | 96935-44-3 |
| MW: | 766 D |
From 77.00€
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Fz25
Item number: Cay37752-10
Fz25 is a triazole-modified sterol and an anticancer agent. It inhibits the proliferation of A2780 ovarian and HT-29 colorectal cancer cells (IC50s = 15.29 and 15.98 µM, respectively). Fz25 decreases the phosphorylation of EGFR and STAT3 in A2780 cells when used at a concentration of 30.58 µM and phosphorylation of...
| Keywords: | (17beta)-3-(phenylmethoxy)-17-(1H-1,2,3-triazol-5-yl)-estra-1,3,5(10)-trien-17-ol |
| Application: | Triazole-modified sterol, anticancer agent |
| CAS | 2762498-70-2 |
| MW: | 429.6 D |
From 45.00€
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113-O16B
Item number: Cay37831-10
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.Formal Name: tetrakis(2-(dodecyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate. CAS Number:...
| Keywords: | tetrakis(2-(dodecyldisulfaneyl)ethyl) 3,3',3'',3'''-(((methylazanediyl)bis(ethane-2,1-diyl))bis(azanetriyl))tetrapropionate |
| Application: | Ionizable cationic lipidoid, LNP formation |
| CAS | 2566523-07-5 |
| MW: | 1447.5 D |
From 151.00€
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IC8
Item number: Cay37986-10
IC8 is an ionizable cationic lipid. It has been used in combination with other lipids for the formation of lipid nanoparticles (LNPs). Immunization with severe acute respiratory coronavirus 2 (SARS-CoV-2) spike glycoprotein mRNA in IC8- and manganese-containing LNPs induces IgG responses to SARS-CoV-2 Delta and...
| Keywords: | 1,1',1'',1'''-((piperazine-1,4-diylbis(propane-3,1-diyl))bis(azanetriyl))tetrakis(tetradecan-2-ol) |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2349307-32-8 |
| MW: | 1049.8 D |
From 151.00€
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AL-A12
Item number: Cay38001-1
AL-A12 is an ionizable cationic amino lipid that has been used in the formation of lipid nanoparticles (LNPs). LNPs containing AL-A12 and encapsulating minicircle DNA that encodes for GFP have been used to induce GFP expression in Huh7 cells. LNPs containing AL-A12 and encapsulating DNA that encodes for RFP have...
| Keywords: | N-dodecyl-N-(3-methoxypropyl)dodecan-1-amine |
| Application: | Ionizable cationic amino lipid, LNP formation |
| MW: | 425.8 D |
From 107.00€
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11-dehydro-2,3-dinor Thromboxane B2-d9
Item number: Cay38254-100
11-dehydro-2,3-dinor Thromboxane B2-d9 (11-dehydro-2,3-dinor TXB2-d9) is intended for use as an internal standard for the quantification of 11-dehydro-2,3-dinor TXB2 (Cay-19510) by GC- or LC-MS. 11-dehydro-2,3-dinor TXB2 is a metabolite of the TXA2 inactive metabolite TXB2 (Cay-19030). It is formed from TXB2 by...
| Keywords: | 11-dehydro-2,3-dinor TXB2-d9,... |
| Application: | GC-MS, LC-MS internal standard, quantification, TXB2 metabolite |
| MW: | 349.5 D |
From 302.00€
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Lipid 222
Item number: Cay38338-1
Lipid 222 is an ionizable cationic amino lipid and a derivative of ALC-0315 (Cay-34337).Formal Name: ((4-hydroxybutyl)azanediyl)bis(octane-8,1-diyl) bis(2-hexyldecanoate). CAS Number: 2985009-46-7. Molecular Formula: C52H103NO5. Formula Weight: 822.4. Purity: >95%. Formulation: (Request formulation change), A...
| Keywords: | ((4-hydroxybutyl)azanediyl)bis(octane-8,1-diyl) bis(2-hexyldecanoate) |
| Application: | Ionizable cationic amino lipid |
| MW: | 822.4 D |
From 54.00€
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Cholesterol-Undecanoate-Glucose Conjugate
Item number: Cay38642-1
Cholesterol-undecanoate-glucose conjugate is a glucose-based lipid conjugate that has been used in the generation of brain-targeted liposomes. It forms a stable, ordered bilayer with phospholipids with the glucose moiety facing outward for the purpose of being recognized by glucose transporter 1 (GLUT1) on the...
| Keywords: | (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-... |
| Application: | Glucose-based lipid conjugate, liposome formation |
| MW: | 825.2 D |
From 54.00€
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TBS-Corey Lactone Aldehyde
Item number: Cay70031-1
TBS-Corey lactone aldehyde is a versatile, hydroxyl-protected intermediate for the synthesis of prostaglandins and prostaglandin analogs. Prostaglandin derivatives with modifications in the alpha chain, the omega chain, or both, are readily accessible from TBS-Corey aldehyde.Formal Name:...
| Keywords: | [3aR-(3aa,4a,5b,6aa)]-5-(tert-butyl-dimethylsilyl)hexahydro-2-oxo-2H-cyclopenta[b]furan-4-carboxaldehyde |
| Application: | Bioactive lipid assays |
| CAS | 64091-14-1 |
| MW: | 284.42 D |
From 300.00€
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9-keto Latanoprost
Item number: Cay9000350-1
9-keto Latanoprost is a derivative of the FP receptor agonist latanoprost (Cay-16812).Formal Name: (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester. CAS Number: 141074-06-8. Molecular Formula: C26H38O5. Formula Weight: 430.6. Purity: >98%....
| Keywords: | (5Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]-5-oxocyclopentyl]-5-heptenoic acid, 1-methylethyl ester |
| Application: | Latanoprost (FP receptor agonist) derivative |
| CAS | 141074-06-8 |
| MW: | 430.6 D |
From 107.00€
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