Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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4-oxo Retinoic Acid
4-oxo Retinoic Acid

Item number: Cay35819-1

4-oxo Retinoic acid is an active metabolite of the vitamin A metabolite and retinoic acid receptor (RAR) ligand all-trans retinoic acid (Cay-11017). It is formed from all-trans retinoic acid by several cytochrome P450 (CYP) isoforms, including CYP1A1, CYP3A7, and CYP26A1. 4-oxo Retinoic acid binds to RARalpha,...
Keywords: 4-keto atRA, 4-oxo RA, all-trans-4-keto Retinoic Acid, all-trans-4-oxo RA, all-trans-4-oxo Retinoic Acid
Application: All-trans retinoic acid active metabolite, retinoic acid receptor (RAR) ligand
CAS 38030-57-8
MW: 314.4 D
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Hexadecanedioic Acid
Hexadecanedioic Acid

Item number: Cay36000-1

Hexadecanedioic acid is a dicarboxylic fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark and soil. It stimulates mitochondrial respiration and decreases the production of reactive oxygen species (ROS) induced by rotenone (Cay-13995) in isolated rat liver mitochondria...
Keywords: 1,16-Hexadecadioic Acid, 1,16-Hexadecanedioic Acid, HDA, NSC 15164, Thapsic Acid, alpha,omega-Hexadecanedioic Acid
Application: Dicarboxylic fatty acid
CAS 505-54-4
MW: 286.4 D
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9,10-Dimethoxypterocarpan-3-O-beta-D-glucoside
9,10-Dimethoxypterocarpan-3-O-beta-D-glucoside

Item number: Cay36192-1

9,10-Dimethoxypterocarpan-3-O-beta-D-glucoside is a flavonoid glycoside that has been found in A. membranaceus and has anti-inflammatory activity. It inhibits LPS-induced production of nitric oxide (NO) in RAW 264.7 macrophages (EC50 = 14.7 µM).Formal Name:...
Keywords: 7-beta-D-glucopyranosyloxy-Astrapterocarpan, Methylnissolin 3-O-glucoside,...
Application: Flavonoid glycoside, antiinflammatory agent
CAS 94367-42-7
MW: 462.5 D
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Pantoic Acid
Pantoic Acid

Item number: Cay36685-10

Pantoic acid is an intermediate in the biosynthesis of D-pantothenic acid (Cay-17288), also known as vitamin B5, and, subsequently, coenzyme A (CoA, Cay-16147, Cay-21499, Cay-21722) in bacteria.Formal Name: (2R)-2,4-dihydroxy-3,3-dimethyl-butanoic acid. CAS Number: 1112-33-0. Synonyms: D-Pantoic Acid, FA 6:0,O2....
Keywords: D-Pantoic Acid, (2R)-2,4-dihydroxy-3,3-dimethyl-butanoic acid
Application: D-pantothenic acid biosynthesis intermediate
CAS 1112-33-0
MW: 148.2 D
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beta-Sitostenone
beta-Sitostenone

Item number: Cay36703-1

beta-Sitostenone is a phytosterol that has been found in A. occidentale and has diverse biological activities. It inhibits basal nitric oxide (NO) production in RAW 264.7 macrophages (IC50 = 15.9 µM). beta-Sitostenone is active against T. evansi (IC50 = 150 nM). It reduces mean blood pressure in normotensive rats...
Keywords: NSC 49082, stigmast-4-en-3-one
Application: Bioactive phytosterol
CAS 1058-61-3
MW: 412.7 D
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Mono-11(Z)-eicosenoin
Mono-11(Z)-eicosenoin

Item number: Cay36860-1

Mono-11(Z)-eicosenoin is a monoacylglycerol that contains 11(Z)-eicosenoic acid (Cay-20606).Formal Name: (Z)-11-eicosenoic acid, monoester with 1,2,3-propanetriol. CAS Number: 62207-88-9. Molecular Formula: C23H44O4. Formula Weight: 384.6. Purity: >95%. Formulation: (Request formulation change), A solution in...
Keywords: (Z)-11-eicosenoic acid, monoester with 1,2,3-propanetriol
Application: Monoacylglycerol
CAS 62207-88-9
MW: 384.6 D
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LC10
LC10

Item number: Cay37000-10

LC10 is a lipidoid derivative of the secondary bile acid lithocholic acid (Cay-20253) that contains two 10-carbon alkyl chains. It has been used in the generation of self-assembling skin-permeable lipid nanoparticles (LNPs). LC10 LNPs inhibit the proliferation of normal human epidermal keratinocytes (NHEKs) when...
Keywords: (R)-N-(2-(didecylamino)ethyl)-4-((3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phena...
Application: Lithocholic acid lipidoid derivative, skin-permeable LNP formation
MW: 735.7 D
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1-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-PE
1-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-PE

Item number: Cay37136-1

1-1(Z)-Octadecenyl-2-adrenoyl-sn-glycero-3-PE is a plasmalogen that contains 1(Z)-octadecenoic acid and adrenic acid (Cay-90300) at the sn-1 and sn-2 positions, respectively. It has been found in L. lactis lipid extracts.Formal Name: 7Z,10Z,13Z,16Z-docosatetraenoic acid,...
Keywords: 18:0p/22:4-PE, 1-O-1(Z)-Octadecenyl-2-Adrenoyl-sn-glycero-3-Phosphatidylethanolamine,...
Application: Plasmalogen
CAS 1390622-95-3
MW: 780.1 D
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7-Ketositosterol
7-Ketositosterol

Item number: Cay37189-10

7-Ketositosterol is a phytosterol and phytosterol oxidation product (POP). It is a thermal oxidation product of sitosterol (24alpha-ethyl cholesterol, Cay-11756). 7-Ketositosterol inhibits the proliferation of HL-60 acute myeloid leukemia (AML) cells (IC50 = 45.6 µM).Formal Name: 3beta-hydroxy-stigmast-5-en-7-one....
Keywords: 7-Oxositosterol, 7-oxo-beta-Sitosterol, 3beta-hydroxy-stigmast-5-en-7-one
Application: Phytosterol, phytosterol oxidation product
CAS 2034-74-4
MW: 428.7 D
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1,2-Dielaidoyl-3-Palmitoyl-rac-glycerol
1,2-Dielaidoyl-3-Palmitoyl-rac-glycerol

Item number: Cay37437-1

1,2-Dielaidoyl-3-palmitoyl-rac-glycerol is a triacylglycerol that contains elaidic acid (Cay-90250) in the sn-1 and sn-2 positions and palmitic acid (Cay-10006627) in the sn-3 position.Formal Name: (9E,9'E)-9-octadecenoic acid, 1,1'-[1-[[(1-oxohexadecyl)oxy]methyl]-1,2-ethanediyl] ester. CAS Number: 68069-77-2....
Keywords: 1,2-Elaidin-3-Palmitin, TG(18:1/18:1/16:0), (9E,9'E)-9-octadecenoic acid,...
Application: Triacylglycerol
CAS 68069-77-2
MW: 859.4 D
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BAMEA-O16B
BAMEA-O16B

Item number: Cay37439-10

BAMEA-O16B is a disulfide bond-containing ionizable cationic lipid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of CRISPR complementary single-guide RNA (sgRNA) and Cas9 mRNA for genome editing in vitro and in vivo. LNPs containing BAMEA-O16B encapsulating Cas9 mRNA and sgRNAs...
Keywords: bis(2-(dodecyldisulfaneyl)ethyl) 3,3'-((3-methyl-9-oxo-10-oxa-13,14-dithia-3,6-diazahexacosyl)azanediyl)dipropionate
Application: Ionizable cationic lipid, LNP formation
CAS 2490668-30-7
MW: 1114.9 D
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omega-azido-C6 Ceramide
omega-azido-C6 Ceramide

Item number: Cay37650-1

omega-azido-C6 Ceramide is a clickable form of C6 ceramide (Cay-62525). It is active against N. meningitidis and N. gonorrhoeae (MIC = 2 µg/ml for both). omega-azido-C6 Ceramide has been used to conjugate alkynylated fluorescent probes to liposomes containing omega-azido-C6 ceramide via a click reaction.Formal Name:...
Keywords: omega-azido-Cer(18:1/6:0), omega-azido-Ceramide (d18:1/6:0), omega-azido-N-hexanoyl-D-erythro-Sphingosine, omega-N3-C6...
Application: C6 ceramide clickable form, click chemistry
CAS 2108102-18-5
MW: 438.7 D
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326 from 345 pages