Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Corey Lactone Benzoate
Corey Lactone Benzoate

Item number: Cay10007983-100

Corey lactone benzoate is a precursor that has been used in the synthesis of prostaglandins (PGs), as well as the agonist of the PGE2 receptor subtype EP4 rivenprost (Cay-13618).Formal Name: (3aR,4S,5R,6aS)-5-(benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one. CAS Number: 39746-00-4. Synonyms:...
Keywords: (-)-Corey Lactone Benzoate, (-)-Corey Lactone Benzoate Alcohol,...
Application: Prostaglandin synthetis precursor
CAS 39746-00-4
MW: 276.3 D
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Prostaglandin D2 serinol amide
Prostaglandin D2 serinol amide

Item number: Cay10192-1

2-Arachidonyl glycerol (2-AG) exhibits cannabinoid (CB) agonist activity at the CB1 receptor, is an important endogenous monoglyceride species, and is thus considered to be the natural ligand for the CB1 receptor. 2-AG can also be sequentially metabolized by COX-2 and specific PG synthases to form PG 2-glyceryl...
Keywords: PGD2-SA, N-[(2-hydroxy-1-hydroxymethyl)ethyl]-11-oxo-9alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-amide
Application: Bioactive lipid assays
CAS 851761-42-7
MW: 425.6 D
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2,3-dinor-8-iso Prostaglandin F1alpha
2,3-dinor-8-iso Prostaglandin F1alpha

Item number: Cay15290-100

DMSO 2,3-dinor-8-iso Prostaglandin F1alpha (2,3-dinor-8-iso PGF1alpha) is an isoprostane and active metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) and the platelet aggregation inhibitor 8-iso PGF2alpha (Cay-16350). It is formed by the non-enzymatic, free radical peroxidation of arachidonic...
Keywords: 2,3-dinor-5,6-dihydro-15-F2t-IsoP, 2,3-dinor-5,6-dihydro-15-F2t-Isoprostane, 2,3-dinor-8-iso PGF1alpha,...
Application: Arachidonic acid / 8-iso PGF2alpha active metabolite
CAS 221664-04-6
MW: 328.4 D
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8-iso-15-keto Prostaglandin F2alpha
8-iso-15-keto Prostaglandin F2alpha

Item number: Cay16390-50

8-iso-15-keto Prostaglandin F2alpha (8-iso-15-keto PGF2alpha) is a metabolite of the isoprostane 8-iso PGF2alpha in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2alpha) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2alpha is...
Keywords: 8-epi-15-keto PGF2alpha, 8-iso-15-keto PGF2alpha, 9alpha,11alpha-dihydroxy-15-oxo-(8beta)-prosta-5Z,13E-dien-1-oic acid
Application: 8-iso PGF2alpha metabolite, vasoconstrictor
CAS 191919-01-4
MW: 352.5 D
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Oxymetholone
Oxymetholone

Item number: Cay21643-1

Oxymetholone is an anabolic androgenic steroid and synthetic derivative of testosterone. Formulations containing oxymetholone are used in the treatment of anemias caused by deficient red cell production. Hepatoxicity is a major adverse effect associated with the use of oxymetholone. Oxymetholone is regulated as a...
Keywords: C.I. 406, NSC 26198, (5alpha,17beta)-17-hydroxy-2-(hydroxymethylene)-17-methyl-androstan-3-one
Application: Anabolic androgenic steroid, synthetic testosterone derivative
CAS 434-07-1
MW: 332.5 D
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Farnesene (mixed isomers)
Farnesene (mixed isomers)

Item number: Cay26891-100

Farnesene (mixed isomers) is a mixture of isomers of the sesquiterpene hydrocarbon farnesene, which has been found in G. hirsutum essential oils. This product may contain trans-beta-farnesene, cis-alpha-farnesene, trans-alpha-farnesene, and bisabolene, among others.Molecular Formula: C15H24. Formula Weight: 204.4....
Keywords: 3,7,11-trimethyl-1,3,6,10-dodecatetraene
Application: Sesquiterpene hydrocarbon
MW: 204.4 D
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Montbretin A
Montbretin A

Item number: Cay30651-1

Montbretin A is an acylated flavonol glycoside that has been found in C. crocosmiiflora and has antidiabetic activity. It inhibits human pancreatic alpha-amylase and B. fibrisolvens amylase B (Kis = 8.1 and 1,600 nM, respectively). Montbretin A reduces blood glucose levels in Zucker diabetic fatty rats when...
Keywords: MbA,...
Application: Acylated flavonol glycoside, antidiabetic agent, pancreatic alpha-amylase inhibitor
CAS 115712-92-0
MW: 1229.1 D
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28-(Poc-amino)betulin
28-(Poc-amino)betulin

Item number: Cay33069-10

28-(Poc-amino)betulin is a terpene and an alkyne derivative of the cholesterol biosynthesis inhibitor betulin (Cay-11041). 28-(Poc-amino)betulin can be used for click chemistry applications.Formal Name: prop-2-yn-1-yl...
Keywords: prop-2-yn-1-yl...
Application: Betulin alkyne derivative, click chemistry
MW: 523.8 D
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Pranoprofen-13C-d3
Pranoprofen-13C-d3

Item number: Cay34009-1

Pranoprofen-13C-d3 is intended for use as an internal standard for the quantification of pranoprofen (Cay-17875) by GC- or LC-MS. Pranoprofen is a non-steroidal anti-inflammatory drug (NSAID) and COX-1 inhibitor (IC50 = 3.1 µM). It decreases B. pertussis-induced production of prostaglandin E2 (PGE2, Cay-14010) in...
Keywords: Pyranoprofen-13C-d3, Y 8004-13C-d3, alpha-methyl-13C-d3-5H-[1]benzopyrano[2,3-b]pyridine-7-acetic acid
Application: GC-MS, LC-MS internal standard, quantification, COX-1 inhibitor
MW: 259.3 D
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Lipid A6
Lipid A6

Item number: Cay35052-10

Lipid A6 is an ionizable cationic and biodegradable alkyne lipid (pKa = 6.65). It has been used with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing lipid A6 and encapsulating mRNA encoding human erythropoietin (EPO) increase and then maintain homeostatic levels...
Keywords: di(dec-3-yn-1-yl) 9-((4-(dimethylamino)butanoyl)oxy)heptadecanedioate
Application: Ionizable cationic, biodegradable alkyne lipid, LNP formation
MW: 702.1 D
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Pyrene
Pyrene

Item number: Cay35168-100

Pyrene is a polycyclic aromatic hydrocarbon (PAH). It has been found in sediments and fish in oil-contaminated mangroves and cigarette smoke. Pyrene inhibits the cytochrome P450 (CYP) isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 41, 7, and 2 nM). It has been conjugated to phospholipids to facilitate the measurement...
Keywords: Benzo[def]phenanthrene, NSC 17534, NSC 66449
Application: Polycyclic aromatic hydrocarbon, CYP1A1/CYP1A2/CYP1B1 inhibitor
CAS 129-00-0
MW: 202.3 D
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Norelgestromin
Norelgestromin

Item number: Cay35243-10

Norelgestromin is an active metabolite of the progestin norgestimate (Cay-16547). Norelgestromin is formed from norgestimate via deacetylation in human liver microsomes. It is an agonist of the progesterone receptor and estrogen receptor alpha (ERalpha, EC50s = 11.1 and 43.4 nM, respectively) and an antagonist of...
Keywords: 17-desacetyl Norgestimate, BRN 4202099, Levonorgestrel oxime, RWJ 10553,...
Application: Norgestimate active metabolite
CAS 53016-31-2
MW: 327.5 D
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