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DLin-MeOH
Item number: Cay41432-10
DLin-MeOH is a synthetic intermediate in the synthesis of the ionizable cationic amino lipid DLin-MC3-DMA (Cay-34364).Formal Name: 6Z,9Z,28Z,31Z-heptatriacontatetraen-19-ol. CAS Number: 1169768-28-8. Molecular Formula: C37H68O. Formula Weight: 528.9. Purity: >98%. Formulation: (Request formulation change), A...
| Keywords: | 6Z,9Z,28Z,31Z-heptatriacontatetraen-19-ol |
| Application: | Ionizable cationic amino lipid DLin-MC3-DMA synthesis intermediate |
| CAS | 1169768-28-8 |
| MW: | 528.9 D |
From 112.00€
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Stearidonoyl Glycine
Item number: Cay9000327-1
The omega-3 polyunsaturated fatty acids (PUFAs) found in fish oils provide cardiovascular benefits. Stearidonic acid is an omega-3 C18:4 PUFA. It is an intermediate in the metabolic pathway leading from alpha-linolenic acid (ALA) to eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Dietary stearidonic acid...
| Keywords: | 2-(6Z,9Z,12Z,15Z)-octadeca-tetraenamidoacetic acid |
| Application: | Bioactive lipid assays |
| MW: | 333.5 D |
From 103.00€
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Azadiradione
Item number: Cay37063-1
Azadiradione is a limonoid that has been found in A. indica and has diverse biological activities. It inhibits heparin-induced tau aggregation by 54.2% in a cell-free assay when used at a concentration of 400 µM. Azadiradione inhibits the tautomerase activity of human, P. falciparum, and P. yoelii migration...
| Keywords: | (5alpha,7alpha,13alpha,17alpha)-7-(acetyloxy)-21,23-epoxy-4,4,8-trimethyl-24-norchola-1,14,20,22-tetraene-3,16-dione |
| Application: | Bioactive limonoid |
| CAS | 26241-51-0 |
| MW: | 450.6 D |
From 409.00€
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YHS-12
Item number: Cay40510-10
YHS-12 is an ionizable cationic lipid (pKa = 6.506) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of siRNA and mRNA in vitro and in vivo. LNPs containing YHS-12 and the macrophage targeting peptide CRVLRSGSC and encapsulating mRNA encoding chimeric antigen receptor targeting...
| Keywords: | (2E)-N1,N4-bis[2-(didodecylamino)ethyl]-2-butenediamide |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2959463-68-2 |
| MW: | 873.5 D |
From 142.00€
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oxLig-1 (technical grade)
Item number: Cay40740-1
oxLig-1 is an omega-carboxylated 7-ketocholesteryl ester and a lipid component of oxidized LDL (oxLDL). It binds to the ligand-binding domain of peroxisome proliferator-activated receptor gamma (PPARgamma), an effect that can be reversed by the PPARgamma agonist troglitazone (Cay-71750), and also binds to CD36, also...
| Keywords: | 7-Ketocholesteryl-9-carboxynonanoate, 3beta-[(8-carboxy-1-oxooctyl)oxy]-cholest-5-en-7-one |
| Application: | OxLDL lipid component |
| CAS | 352523-18-3 |
| MW: | 570.8 D |
From 186.00€
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Lipid 29d
Item number: Cay40913-1
Lipid 29d is an unsaturated ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. Intravenous administration of LNPs containing lipid 29d and encapsulating mRNA encoding a luciferase reporter induce bioluminescence in the lungs and spleen of...
| Keywords: | N-[3-(dimethylamino)propyl]-4,5,6,7-tetrahydro-6-[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]-2-[[(9Z,12Z)-1-oxo-9,12-octadecad... |
| Application: | Unsaturated ionizable cationic lipid, LNP formation |
| CAS | 2921586-67-4 |
| MW: | 807.3 D |
From 112.00€
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N-Cholyl-L-Alanine
Item number: Cay40928-100
N-Cholyl-L-alanine is a bile acid amidate. It has been found in human fecal samples.Formal Name: N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]-L-alanine. CAS Number: 18416-54-1. Synonyms: N-Cholyl-Ala. Molecular Formula: C27H45NO6. Formula Weight: 479.7. Purity: >95%. Formulation: (Request...
| Keywords: | N-Cholyl-Ala, N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]-L-alanine |
| Application: | Bile acid amidate |
| CAS | 18416-54-1 |
| MW: | 479.7 D |
186.00€
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N-Cholyl-L-Leucine
Item number: Cay40930-100
N-Cholyl-L-leucine is a bile acid amidate. It has been found in fecal samples from extremely premature infants with mild or severe brain injuries. N-Cholyl-L-leucine has been used as a standard for the detection of endogenous bile acid amidates in human plasma and fecal samples.Formal Name:...
| Keywords: | N-Cholyl-Leu, N-[(3alpha,5beta,7alpha,12alpha)-3,7,12-trihydroxy-24-oxocholan-24-yl]-L-leucine |
| Application: | Bile acid amidate |
| CAS | 22154-46-7 |
| MW: | 521.7 D |
From 110.00€
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L-369
Item number: Cay41232-1
L-369 is an ionizable cationic lipid.Formal Name: 9-[4-(dimethylamino)-1-oxobutoxy]-heptadecanedioic acid, 1,17-bis(3-pentyloctyl) ester. CAS Number: 1443522-24-4. Synonyms: Lipid 369. Molecular Formula: C49H95NO6. Formula Weight: 794.3. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol....
| Keywords: | Lipid 369, 9-[4-(dimethylamino)-1-oxobutoxy]-heptadecanedioic acid, 1,17-bis(3-pentyloctyl) ester |
| Application: | Ionizable cationic lipid |
| CAS | 1443522-24-4 |
| MW: | 794.3 D |
From 186.00€
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Q1-SM-102 (iodide)
Item number: Cay41239-1
Q1-SM-102 is a cationic quaternary ammonium lipid derivative of the ionizable cationic lipid SM-102 (Cay-33474) that has been used in the generation of lipid nanoparticles (LNPs) for use in vivo. LNPs containing Q1-SM-102 and SM-102 as a cationic lipid pair (CLP) and encapsulating mRNA encoding a luciferase reporter...
| Keywords: | Q1-CAY10779, Q1-Lipid H, Q1-LNP-102,... |
| Application: | Cationic quaternary ammonium lipid SM-102 derivative, LNP formation |
| MW: | 852.1 D |
From 112.00€
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C12-TLRa
Item number: Cay41338-10
C12-TLRa is an adjuvant lipidoid (pKa = 6.42) with toll-like receptor 7/8 (TLR7/8) agonist activity. Lipid nanoparticles (LNPs) containing C12-TLRa as a partial replacement for the ionizable lipidoid C12-113 (Cay-39335) and encapsulating luciferase mRNA exhibit TLR7 agonist activity in HEK reporter cells and induce...
| Keywords: | C12-Toll-Like Receptor a, 1,1'-((4-((4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)methyl)benzyl)azanediyl)bis(dodecan-2-ol) |
| Application: | Adjuvant lipidoid, TLR7/8 agonist |
| MW: | 728.1 D |
From 248.00€
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N-butyl Lithocholic Acid
Item number: Cay41397-1
N-butyl Lithocholic acid is a derivative of the secondary bile acid lithocholic acid (Cay-20253). Lipid nanoparticles (LNPs) containing N-butyl lithocholic acid and encapsulating an mRNA vaccine expressing influenza hemagglutinin exhibit less heart, spleen, and liver toxicity than LNPs containing cholesterol...
| Keywords: | N-butyl LCA, N-butyl Lithocholate, (3alpha,5beta)-3-hydroxy-cholan-24-oic acid, butyl ester |
| Application: | Secondary bile acid lithocholic acid derivative, LNP formation |
| CAS | 135013-42-2 |
| MW: | 432.7 D |
From 53.00€
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