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Rosuvastatin EP Impurity A (calcium salt)
Item number: Cay35686-10
Rosuvastatin EP impurity A is a potential impurity in commercial preparations of the HMG-CoA reductase inhibitor rosuvastatin.Formal Name: 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid, hemicalcium salt. CAS Number:...
| Keywords: | 7-[4-(4-fluorophenyl)-2-[[(2-hydroxy-2-methylpropyl)sulfonyl]methylamino]-6-(1-methylethyl)-5-pyrimidinyl]-3,5-dihydroxy-6... |
| Application: | Commercial rosuvastatin preparation potential impurity |
| CAS | 1714147-47-3 |
| MW: | 558.7 D |
From 118.00€
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1-Docosahexaenoyl-rac-glycerol
Item number: Cay35871-1
1-Docosahexaenoyl-rac-glycerol is a monoacylglycerol that contains docosahexaenoic acid (DHA, Cay-90310, Cay-17950) at the sn-1 position. It reduces smooth muscle tension induced by endothelin-1 (ET-1) in isolated human pulmonary arteries (HPAs) when used at concentrations ranging from 1 to 30 µM....
| Keywords: | 1-Docosahexaenoin, MAG-DHA, MG(22:6/0:0/0:0), 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid, 2,3-dihydroxypropyl ester |
| Application: | DHA containg monoacylglycerol |
| CAS | 140670-40-2 |
| MW: | 402.6 D |
From 38.00€
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Annaosanchun
Item number: Cay37572-1
Annaosanchun is a synthetic sterol and neuroprotectant agent. It increases the viability of, and the levels of ATP and the mitochondrial membrane potential in, hypoxia-exposed and reoxygenated primary rat cortical neurons when used at concentrations of 0.1, 0.3, and 1 µM. Annaosanchun (10 µM) prevents...
| Keywords: | androstane-3beta,5alpha,6beta-triol |
| Application: | Synthetic sterol, neuroprotective agent |
| CAS | 4725-51-3 |
| MW: | 308.5 D |
From 38.00€
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PL1
Item number: Cay38647-1
PL1 is a multi-tail ionizable cationic phospholipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing PL1 and encapsulating mRNA encoding the co-stimulatory receptor CD137 or OX40 increase T cell antitumor immunity in various...
| Keywords: | di(octan-3-yl) 9,9'-((3-((3-((diethoxyphosphoryl)oxy)propyl)(9-(octan-3-yloxy)-9-oxononyl)amino)propyl)azanediyl)dinonanoate |
| Application: | Multi-tail ionizable cationic phospholipid, LNP formation |
| CAS | 2274812-94-9 |
| MW: | 1073.6 D |
From 118.00€
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15(R)-HODE
Item number: Cay38710-100
15(R)-HODE is an oxylipin that has been found in oat seeds.Formal Name: 15R-hydroxy-9Z,12Z-octadecadienoic acid. CAS Number: 177931-23-6. Synonyms: 15(R)-9(Z),12(Z)-HODE, 15(R)-Hydroxyoctadecadienoic Acid, 15(R)-hydroxy-9(Z),12(Z)-ODE, 15(R)-hydroxy-cis-9,12-Octadecadienoic Acid, Avenoleic Acid, FA 18:2. Molecular...
| Keywords: | 15(R)-9(Z),12(Z)-HODE, 15(R)-hydroxy-cis-9,12-Octadecadienoic Acid, 15(R)-hydroxy-9(Z),12(Z)-ODE,... |
| Application: | Oxylipin |
| CAS | 177931-23-6 |
| MW: | 296.5 D |
From 260.00€
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N-Hexadecyl-N,N-dimethylhexadecan-1-aminium (bromide)
Item number: Cay38871-1
N-Hexadecyl-N,N-dimethylhexadecan-1-aminium is a cationic lipid that has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs). Administration of LNPs containing N-hexadecyl-N,N-dimethylhexadecan-1-aminium and encapsulating mRNA encoding a luciferase reporter increase fluorescence...
| Keywords: | DC-1-16, Dihexadecyldimethylammonium bromide, N-hexadecyl-N,N-dimethyl-1-hexadecanaminium, monobromide |
| Application: | Cationic lipid, LNP formation |
| CAS | 70755-47-4 |
| MW: | 574.9 D |
83.00€
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Stearda
Item number: Cay38973-10
Stearda is an endogenous fatty acid amide composed of the catecholamine dopamine (Cay-36532, Cay-21992) conjugated to the long-chain saturated fatty acid stearic acid (Cay-10011298). It is an inhibitor of 5-lipoxygenase (5-LO, IC50 = 16 nM). Stearda is cytotoxic to K562 chronic myeloid leukemia cells, HOS...
| Keywords: | N-octadecanoyl Dopamine, N-Stearoyl Dopamine, N-[2-(3,4-dihydroxyphenyl)ethyl]-octadecanamide |
| Application: | Endogenous fatty acid amide, arachidonate 5-lipoxygenase inhibitor |
| CAS | 105955-10-0 |
| MW: | 419.6 D |
From 97.00€
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N-Linoleoyl-DPPE (ammonium salt)
Item number: Cay39193-1
N-Linoleoyl-DPPE is an N-acyl-phosphatidylethanolamine (NAPE).Formal Name: (R)-2,3-bis(palmitoyloxy)propyl (2-((9Z,12Z)-octadeca-9,12-dienamido)ethyl) phosphate, monoammonium salt. Synonyms: NAPE(16:0/16:0/18:2), N-Linoleoyl-1,2-Dipalmitoyl-3-PE, N-Linoleoyl-1,2-Dipalmitoyl-3-Phosphoethanolamine,...
| Keywords: | NAPE(16:0/16:0/18:2), N-Linoleoyl-1,2-Dipalmitoyl-3-PE, N-Linoleoyl-1,2-Dipalmitoyl-3-Phosphatidylethanolamine,... |
| Application: | N-acyl-phosphatidylethanolamine (NAPE) |
| MW: | 971.4 D |
From 44.00€
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Anthraflavic Acid
Item number: Cay39246-1
Anthraflavic acid is a polyketide synthase-derived anthraquinone that has been found in Rhei Rhizoma and has diverse biological activities. It inhibits alpha-amylase in a cell-free assay (IC50 = 198.3 nM) and cytochrome P450 activity induced by a mixture of polychlorinated biphenyls (PCBs) in rat hepatic microsomes....
| Keywords: | 2,6-DHAQ, 2,6-Dihydroxyanthraquinone, NSC 33531, 2,6-dihydroxy-9,10-anthracenedione |
| Application: | Bioactive anthraquinone |
| CAS | 84-60-6 |
| MW: | 240.2 D |
From 44.00€
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Mogroside IIIE
Item number: Cay39286-1
Mogroside IIIE is a cucurbitane glycoside that has been found in S. grosvenorii and has anti-inflammatory activity. It inhibits LPS-induced secretion of IL-1beta, IL-6, and Tnf-alpha from, as well as LPS-induced increases in toll-like receptor 4 (TLR4) levels in, RAW 264.7 macrophages when used at a concentration of...
| Keywords: | MGIIIE, (3beta,9beta,10alpha,11alpha,24R )-3-(beta-D-glucopyranosyloxy)-11,25-dihydroxy-9-methyl-19-norlanost-5-en-24-yl... |
| Application: | Cucurbitane glycoside, antiinflammatory agent |
| CAS | 88901-37-5 |
| MW: | 963.2 D |
From 97.00€
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TNT-b10
Item number: Cay39294-1
TNT-b10 is an ionizable cationic lipidoid that has been used in the formation of lipid-like nanoparticles (LLNs). LLNs containing TNT-b10 and encapsulating an mRNA reporter increase luminescence in Hep3B liver cancer cells.Formal Name:...
| Keywords: | 1,3,5-tris(2-((2-hydroxydodecyl)(methyl)amino)ethyl)-1,3,5-triazinane-2,4,6-trione |
| Application: | Lipidoid, LLN formation |
| MW: | 853.3 D |
From 118.00€
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C3-K2-E14
Item number: Cay39323-1
C3-K2-E14 is an ionizable cationic lipid (pKa = 5.5). It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA or siRNA in vitro and in vivo. LNPs containing C3-K2-E14 and encapsulating siRNA targeting the gene encoding colony-stimulating factor 1 (Csf1) reduce the percentage of...
| Keywords: | 3,3'-(propylazanediyl)bis(N-(2-(bis(2-hydroxytetradecyl)amino)ethyl)propanamide) |
| Application: | Ionizable cationic lipid, LNP formation |
| CAS | 2933215-86-0 |
| MW: | 1136.9 D |
From 62.00€
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