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Apocarotenal
Item number: Cay37231-100
Apocarotenal is a carotenoid that has been found in D. draco and has genotoxic and antioxidant activities and is an active metabolite of the antioxidant terpenoid beta-carotene (Cay-16837). It is formed from beta-carotene by beta-carotene 9',10'-oxygenase 2 (BCO2). Apocarotenal (100 µM) scavenges free radicals in a...
| Keywords: | trans-beta-Apo-8'-carotenal, Food Orange 6,... |
| Application: | Carotenoid, genotoxic agent, antioxidant agent, active beta-carotene metabolite |
| CAS | 1107-26-2 |
| MW: | 416.6 D |
From 123.00€
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4-Biphenylacetic Acid
Item number: Cay38116-100
4-Biphenylacetic acid is a non-steroidal anti-inflammatory drug (NSAID) and an active metabolite of the prodrug fenbufen (Cay-28851). It inhibits prostaglandin E2 (PGE2, Cay-14010) synthesis in a cell-free assay (IC50 = 3.2 µM). In vivo, 4-biphenylacetic acid (2 mg/kg) suppresses UV-induced erythema in guinea pigs....
| Keywords: | p-Biphenylacetic Acid, Cl-83544, Felbinac, LY601017, NSC 16284, [1,1'-biphenyl]-4-acetic acid |
| Application: | NSAID, active fenbufen metabolite |
| CAS | 5728-52-9 |
| MW: | 212.2 D |
From 53.00€
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IMM-H007
Item number: Cay38774-1
IMM-H007 is an activator of AMP-activated protein kinase (AMPK) and an antagonist of TGF-beta1. It increases AMPK activity in HepG2 cell lysates when used at concentrations ranging from 1 to 100 µM. IMM-H007 binds to TGF-beta1 (Kd = 0.2098 µM) and inhibits the binding of TGF-beta1 to TGF-beta receptor type 2...
| Keywords: | N-(3-hydroxyphenyl)-adenosine 2',3',5'-triacetate |
| Application: | AMPK activator, TGF-beta1 antagonist |
| CAS | 1221412-23-2 |
| MW: | 485.5 D |
From 77.00€
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5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-2H-tetrazole
Item number: Cay38780-1
5-(4'-(Azidomethyl)(1,1'-biphenyl)-2-yl)-2H-tetrazole (AZTT) is a potential impurity found in commercial preparations of tetrazole-containing sartans, including losartan, irbesartan, and valsartan.CAS Number: 152708-24-2. Synonyms: AZTT. Molecular Formula: C14H11N7. Formula Weight: 277.3. Purity: >95%. Formulation:...
| Keywords: | AZTT |
| Application: | Potential impurity in commercial tetrazole-containing sartan preparations |
| CAS | 152708-24-2 |
| MW: | 277.3 D |
From 53.00€
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1,2-Dioleoyl-3-trimethylammoniumpropane (methyl sulfate)
Item number: Cay38905-10
CCCCCCCC/C=C\CCCCCCCC(OC(C[N+](C)(C)C)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O.[O-]S(=O)(OC)=OFormal Name: N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-1-propanaminium, monomethyl sulfate. CAS Number: 144189-73-1. Synonyms: DOTAP. Molecular Formula: C42H80NO4 . CH3SO4. Formula Weight: 774.2. Purity: >98%....
| Keywords: | DOTAP, N,N,N-trimethyl-2,3-bis[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]-1-propanaminium, monomethyl sulfate |
| Application: | Cationic lipid, cationic liposome-forming compound |
| CAS | 144189-73-1 |
| MW: | 774.2 D |
From 49.00€
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Phellopterin
Item number: Cay38965-1
Phellopterin is a furanocoumarin that has been found in A. dahurica and has diverse biological activities. It is an antagonist of GABAA receptors (IC50 = 360 nM for the rat receptor). Phellopterin (20 µM) decreases LPS-induced secretion of prostaglandin E2 (PGE2, Cay-14010) from primary rat peritoneal macrophages....
| Keywords: | NSC 152469, 7-butyl-5-hydroxy-2-methyl-2-(4-methyl-3-penten-1-yl)-2H-1-benzopyran-6-carboxylic acid |
| Application: | Bioactive furanocoumarin |
| CAS | 2543-94-4 |
| MW: | 300.3 D |
From 131.00€
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Typhaneoside
Item number: Cay38970-10
Typhaneoside is a flavonoid glycoside that has been found in T. angustifolia and has diverse biological activities. It decreases colony size and induces ferroptosis and cell cycle arrest at the G2/M phase in Kasumi-1 and NB4 leukemia cells when used at a concentration of 40 µM. Typhaneoside (70 µM) reduces...
| Keywords: | 3-[(O-6-deoxy-alpha-L-mannopyranosyl-(1->2)-O-[6-deoxy-alpha-L-mannopyranosyl-(1->6)]-beta-D-glucopyranosyl)oxy]-5,7-dihyd... |
| Application: | Bioactive flavonoid glycoside |
| CAS | 104472-68-6 |
| MW: | 770.7 D |
From 73.00€
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PAMAM Dendrimer G2.0 Amine (water solution)
Item number: Cay39072-1
PAMAM dendrimer G2.0 amine (PAMAM G2.0) is a polyamidoamine (PAMAM) dendrimer with amine termini. It is approximately 29 Å in diameter and has 16 surface groups. PAMAM G2.0 (15 mg/ml) in combination with erythromycin (Cay-16486) enhances the solubility and antibacterial activity of erythromycin against S. aureus. It...
| Keywords: | PAMAM G2.0, Polyamidoamine Dendrimer G2.0, 2-propenoic acid, polymer with 1,2-ethanediamine, methyl ester |
| Application: | Amine-terminated PAMAM dendrimer |
| CAS | 26937-01-9 |
| MW: | 3256.2 D |
From 133.00€
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PAMAM Dendrimer G0.5 Carboxylate (sodium salt) (water...
Item number: Cay39104-1
PAMAM dendrimer G0.5 carboxylate (PAMAM G0.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini. It is approximately 27.9 Å in diameter in water and has 8 surface groups. Conjugates of PAMAM G0.5 with the active fragment of the DNA cross-linking agent oxaliplatin (Cay-13106) are cytotoxic to A2780...
| Keywords: | Polyamidoamine Dendrimer G0.5 Carboxylate, PAMAM G0.5 Carboxylate,... |
| Application: | Carboxylate-terminated PAMAM dendrimer |
| CAS | 339334-01-9 |
| MW: | 1269.1 D |
From 112.00€
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PAMAM Dendrimer G1.5 Carboxylate (sodium salt) (water...
Item number: Cay39106-1
PAMAM dendrimer G1.5 carboxylate (PAMAM G1.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini. It is approximately 36.2 Å in diameter in water and has 12 surface groups. PAMAM G1.5 (10 µM) inhibits plaque formation induced by Middle East respiratory syndrome coronavirus (MERS-CoV) in Vero cells....
| Keywords: | PAMAM G1.5 Carboxylate, Polyamidoamine Dendrimer G1.5 Carboxylate,... |
| Application: | Carboxylate-terminated PAMAM dendrimer |
| CAS | 251970-28-2 |
| MW: | 2934.6 D |
From 161.00€
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PAMAM Dendrimer G2.5 Carboxylate (sodium salt) (water...
Item number: Cay39107-1
PAMAM dendrimer G2.5 carboxylate is a polyamidoamine (PAMAM) dendrimer with carboxylate termini (PAMAM G2.5). It is approximately 48.3 Å in diameter in water and has 24 surface groups. PAMAM G2.5 binds to cytochrome c and decreases its hydrolysis by chymotrypsin by approximately ~30% in a cell-free assay when used...
| Keywords: | PAMAM G2.5 Carboxylate, Polyamidoamine Dendrimer G2.5 Carboxylate |
| Application: | Carboxylate-terminated PAMAM dendrimer |
| CAS | 202009-65-2 |
| MW: | 6265.6 D |
From 216.00€
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PAMAM Dendrimer G3.5 Carboxylate (sodium salt) (water...
Item number: Cay39108-1
PAMAM dendrimer G3.5 carboxylate (PAMAM G3.5) is a polyamidoamine (PAMAM) dendrimer with carboxylate termini that has been used as a drug delivery system in vitro and in vivo. It is approximately 66.1 Å in diameter in water and has 48 surface groups. PAMAM G3.5 is active against E. coli (IC50 = 22 mg/ml) and...
| Keywords: | PAMAM G3.5 Carboxylate, Polyamidoamine Dendrimer G3.5 Carboxylate |
| Application: | Carboxylate-terminated PAMAM dendrimer |
| CAS | 192948-77-9 |
| MW: | 12927.7 D |
From 320.00€
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