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(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-car...
Item number: Cay39257-1
(R)-2-(3-(2-Ethoxyphenoxy)piperidin-1-yl)pyrimidine-5-carboxylic acid is an intermediate in the synthesis of the diacylglycerol acyltransferase 2 (DGAT-2) inhibitor ervogastat (Cay-37929).Formal Name: 2-[(3R)-3-(2-ethoxyphenoxy)-1-piperidinyl]-5-pyrimidinecarboxylic acid. CAS Number: 1809064-89-8. Molecular Formula:...
| Keywords: | 2-[(3R)-3-(2-ethoxyphenoxy)-1-piperidinyl]-5-pyrimidinecarboxylic acid |
| Application: | Ervogastat synthesis intermediate |
| CAS | 1809064-89-8 |
| MW: | 343.4 D |
From 78.00€
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C12-113
Item number: Cay39335-10
C12-113 is an ionizable cationic lipidoid. It has been used in combination with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA encoding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein in mice.Formal Name:...
| Keywords: | 1,1',1'',1'''-[(methylimino)bis(2,1-ethanediylnitrilo)]tetrakis-2-dodecanol |
| Application: | Ionizable cationic lipidoid, LNP formation |
| CAS | 1220890-27-6 |
| MW: | 854.5 D |
From 157.00€
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(±)-Linalool-d3
Item number: Cay9004273-10
(±)-Linalool-d3 is intended for use as an internal standard for the quantification of (±)-linalool (Cay-21575) by GC- or LC-MS. (±)-Linalool is a monoterpene alcohol that has been found in C. sativa, C. indica, and hemp with diverse biological activities. It induces cell cycle arrest at the G0/G1 and G2M phase in...
| Keywords: | dl-Linalool-d3, 3,7-dimethyl-1,6-octadien-1,1,2-d3-3-ol |
| Application: | GC-MS, LC-MS internal standard, quantification, bioactive monoterpene alcohol |
| CAS | 1216673-02-7 |
| MW: | 157.3 D |
390.00€
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m-Coumaric Acid
Item number: Cay37236-1
m-Coumaric acid is an active metabolite of various polyphenols, including chlorogenic acid (Cay-70930) and rosmarinic acid (Cay-70900). It inhibits cumene hydroperoxide-induced oxidation of DNA (IC50 = 54.7 µM). m-Coumaric acid (10 µM) induces neurite outgrowth of fetal rat hippocampal neurons. It induces apoptosis...
| Keywords: | m-hydroxy Cinnamic Acid, meta-Coumaric Acid, meta-hydroxy Cinnamic Acid, 3-Coumaric Acid, 3-hydroxy Cinnamic Acid, NSC... |
| Application: | Active polyphenol metabolite |
| CAS | 588-30-7 |
| MW: | 164.2 D |
From 40.00€
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Tri-Salicylic Acid
Item number: Cay37348-100
Tri-salicylic acid is a degradation product of aspirin. It is formed under conditions of thermal stress.Formal Name: 2-[(2-hydroxybenzoyl)oxy]-benzoic acid, 2-carboxyphenyl ester. CAS Number: 85531-17-5. Molecular Formula: C21H14O7. Formula Weight: 378.3. Purity: >98%. Formulation: (Request formulation change), A...
| Keywords: | 2-[(2-hydroxybenzoyl)oxy]-benzoic acid, 2-carboxyphenyl ester |
| Application: | Aspirin degradation product |
| CAS | 85531-17-5 |
| MW: | 378.3 D |
From 134.00€
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Glabrol
Item number: Cay37367-1
Glabrol is a flavonoid that has been found in G. glabra and has diverse biological activities. It inhibits neuraminidase (NA) activity in oseltamivir-sensitive and -resistant H1N1 influenza strains (IC50s = 0.51 and 14.1 µM, respectively), as well as protein tyrosine phosphatase 1B (PTP1B), acyl-coenzyme...
| Keywords: | (2S)-2,3-dihydro-7-hydroxy-2-[4-hydroxy-3-(3-methyl-2-buten-1-yl)phenyl]-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one |
| Application: | Bioactive flavonoid |
| CAS | 59870-65-4 |
| MW: | 392.5 D |
From 181.00€
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1,2-Stearoyl-3-trimethylammoniumpropane (chloride)
Item number: Cay37404-100
1,2-Stearoyl-3-trimethylammoniumpropane (DSTAP) is a cationic lipid that has been used in the formation of lipid nanoparticles (LNPs). Intraperitoneal administration of LNPs containing DSTAP and encapsulating resiquimod (R-848, Cay-14806) increases peritoneal fluid levels of IFN-alpha, the number of tumor-associated...
| Keywords: | 18:0 TAP, DSTAP, N,N,N-trimethyl-2,3-bis[(1-oxooctadecyl)oxy]-1-propanaminium, monochloride |
| Application: | Cationic lipid, LNP formation |
| CAS | 220609-41-6 |
| MW: | 702.6 D |
From 259.00€
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Dioleyldimethylammonium (chloride)
Item number: Cay38797-1
Dioleyldimethylammonium chloride (DODAC) is a cationic lipid that has been used as a transfection reagent. Liposomes containing DODAC and dioleoylphosphatidylethanolamine (DOPE) and encapsulating a plasmid DNA reporter induce reporter gene expression in C2C12 mouse skeletal muscle myoblasts.Formal Name:...
| Keywords: | Dimethyldioleylammonium chloride, DODAC, N,N-Dioleyl-N,N-dimethylammonium chloride,... |
| Application: | Cationic lipid, transfection reagent |
| CAS | 7212-69-3 |
| MW: | 582.5 D |
From 49.00€
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1,2-Dimyristoyl-3-trimethylammoniumpropane (chloride)
Item number: Cay38906-100
1,2-Dimyristoyl-3-trimethylammoniumpropane (DMTAP) is a cationic lipid that has been used as a transfection reagent. Lipid nanodiscs containing DMTAP and dimyristoylphosphatidylcholine (DMPC) and bound to siRNA against GAPDH reduce GAPDH enzymatic activity in HepG2 cells.Formal Name:...
| Keywords: | 14:0 TAP, DMTAP, N,N,N-trimethyl-2,3-bis[(1-oxotetradecyl)oxy]-1-propanaminium, monochloride |
| Application: | Cationic lipid, transfection reagent |
| CAS | 197974-74-6 |
| MW: | 590.4 D |
From 99.00€
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(±)7(S),8(S)-DiHDoTrE
Item number: Cay38934-25
(±)7(S),8(S)-DiHDoTrE is an oxylipin.Formal Name: 7S,8S-dihydroxy-10Z,13Z,16Z-docosatrienoic acid. Synonyms: (±)7(S),8(S)-DHDT. Molecular Formula: C22H38O4. Formula Weight: 366.5. Purity: >95%. Formulation: (Request formulation change), A solution in ethanol. Solubility: DMSO: 10 mg/ml, Ethanol: 10 mg/ml. SMILES:...
| Keywords: | (±)7,8-DHDT, (±)-Dihydroxydocosatrienoic Acid, 7,8-dihydroxy-10Z,13Z,16Z-docosatrienoic acid |
| Application: | Oxylipin |
| MW: | 366.5 D |
From 166.00€
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Lipid R6
Item number: Cay39130-10
Lipid R6 is an ionizable cationic lipid.Formal Name: 2-((3-(diethylamino)propyl)amino)-N-undecylheptadecanamide. Molecular Formula: C35H73N3O. Formula Weight: 552.0. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 10 mg/ml. SMILES:...
| Keywords: | 2-((3-(diethylamino)propyl)amino)-N-undecylheptadecanamide |
| Application: | Ionizable cationic lipid |
| MW: | 552 D |
From 239.00€
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CP 346,086
Item number: Cay39156-1
CP 346,086 is an inhibitor of microsomal triglyceride transfer protein (MTTP, IC50 = 2 nM). It inhibits apolipoprotein B (ApoB) and triglyceride secretion in HepG2 cells (IC50 = 2.6 nM for both). CP 346,086 (10 mg/kg) lowers plasma triglyceride levels, as well as plasma total, VLDL, and LDL cholesterol levels in...
| Keywords: | N-[1,2,3,4-tetrahydro-2-(1H-1,2,4-triazol-5-ylmethyl)-6-isoquinolinyl]-4'-(trifluoromethyl)- [1,1'-biphenyl]-2-carboxamide |
| Application: | MTTP (microsomal triglyceride transfer protein) inhibitor |
| CAS | 186390-48-7 |
| MW: | 477.5 D |
From 42.00€
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