No results were found for the filter!
C12 NBD Ceramide (d18:1/12:0)
Item number: Cay10007958-1
C12 NBD ceramide (d18:1/12:0) is a long-chain fluorescent ceramide analog that can be used for the measurement of alkaline and neutral ceramidase activity. It is hydrolyzed efficiently by alkaline ceramidase from P. aeruginosa and by neutral ceramidase from mouse liver. In addition, alkaline and neutral ceramidases...
| Keywords: | N-C12-NBD-D-erythro-Sphingosine, NBD Cer(d18:1/12:0), NBD Ceramide (d18:1/12:0),... |
| Application: | Bioactive lipid assays |
| CAS | 202850-01-9 |
| MW: | 659.9 D |
From 266.00€
*
cis-Parinaric Acid
Item number: Cay71430-1
cis-Parinaric acid is a naturally occurring polyunsaturated fatty acid containing an unusual conjugated (Z,E,E,Z) tetraene. This chromophore provides for a natural fluorescence at 432 nm with an excitation wavelength at 320 nm. cis-Parinaric acid occurs naturally in the seeds of the Makita tree, a tropical...
| Keywords: | alpha-Parinaric Acid, 9Z,11E,13E,15Z-octadecatetraenoic acid |
| Application: | Phospholipase activity measurement |
| CAS | 18427-44-6 |
| MW: | 276.4 D |
From 382.00€
*
Lipid-based Drug Delivery Tools
1,2-Distearoyl-sn-glycero-3-PC
Item number: Cay15100-1
1,2-Distearoyl-sn-glycero-3-PC (1,2-DSPC) is a phospholipid containing the saturated long-chain (18:0) stearic acid inserted at the sn-1 and sn-2 positions. It is commonly used in the generation of micelles, liposomes, and other types of artificial membranes. The transition temperature of 1,2-DSPC is approximately...
| Keywords: | 1,2-Distearoyl-sn-glycero-3-Phosphocholine, 1,2-DSPC, Coatsome MC 8080, 1,2-distearoyl-sn-glycero-3-phosphatidylcholine |
| Application: | Phospholipid |
| CAS | 816-94-4 |
| MW: | 790.2 D |
From 83.00€
*
20-hydroxy Leukotriene B4
Item number: Cay20190-25
20-hydroxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. 20-hydroxy LTB4 is not only much less active (~5%) compared to LTB4 in causing degranulation of PMNL, but actually inhibits LTB4-induced degranulation of human neutrophils (Ki =...
| Keywords: | 20-hydroxy LTB4, 5S,12R,20-trihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 79516-82-8 |
| MW: | 352.5 D |
From 251.00€
*
Lipid-based Drug Delivery Tools
ALC-0159
Item number: Cay34336-25
ALC-0159 is a lipid excipient. Formulations containing ALC-0159 have been used in the development of lipid nanoparticles (LNPs) for the delivery of mRNA-based vaccines.Formal Name: alpha-[2-(ditetradecylamino)-2-oxoethyl]-omega-methoxy-poly(oxy-1,2-ethanediyl). CAS Number: 1849616-42-7. Synonyms:...
| Keywords: | alpha-[2-(ditetradecylamino)-2-oxoethyl]-omega-methoxy-poly(oxy-1,2-ethanediyl) |
| Application: | Lipid excipient, mRNA-based vaccine delivery |
| CAS | 1849616-42-7 |
From 147.00€
*
(±)5-HEPE
Item number: Cay32200-25
(±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine...
| Keywords: | (±)-5-hydroxy-6E,8Z,11Z,14Z,17Z-eicosapentaenoic acid |
| Application: | Bioactive lipid studies |
| CAS | 83952-40-3 |
| MW: | 318.5 D |
From 174.00€
*
MEL-A
Item number: Cay33858-25
MEL-A is a glycolipid biosurfactant that is produced from vegetable oils by Pseudozyma yeasts. Mixtures of MEL-A isoforms have been used as moisturizing agents in cosmetics, as well as to improve the low-temperature fluidity of biodiesel and hydrocarbon fuels. This product is a mixture of MEL-A isoforms with...
| Keywords: | Mannosylerythritol Lipid A,... |
| Application: | Glycolipid biosurfactant |
547.00€
*
Serotonin (hydrochloride)
Item number: Cay14332-50
Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
| Keywords: | 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride |
| Application: | Monoamine neurotransmitter |
| CAS | 153-98-0 |
| MW: | 212.7 D |
From 75.00€
*
(±)-Jasmonic Acid-Isoleucine
Item number: Cay10740-10
(±)-Jasmonic acid-isoleucine (JA-Ile) is a mixture that contains two of the four possible stereoisomers of JA-Ile: (1R,2R)- and (1S,2S)-JA-Ile. JA-Ile is a plant hormone formed by the conjugation of jasmonic acid (Cay-88300) and the amino acid isoleucine. JA-Ile signals through a co-receptor complex composed of the...
| Keywords: | (±)-JA-Ile, N-[2-[(1R,2R)-3-oxo-2-(2Z)-2-penten-1-ylcyclopentyl]acetyl]-L-isoleucine,... |
| MW: | 323.4 D |
From 58.00€
*
Bromoenol lactone
Item number: Cay70700-5
BEL is a selective, potent, irreversible, mechanism-based inhibitor of myocardial cytosolic calcium-independent phospholipase A2 (iPLA2) with a Ki value of 180 nM. BEL also inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM and is an effective enzyme-activated irreversible...
| Keywords: | BEL, Haloenol lactone, HELSS, 6E-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyran-2-one |
| Application: | iPLA2 inhibitor |
| CAS | 88070-98-8 |
| MW: | 317.2 D |
From 178.00€
*
Lipid-based Drug Delivery Tools
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC
Item number: Cay10172-25
1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. It increases the production of reactive oxygen species (ROS) and decreases superoxide dismutase (SOD) and endothelial nitric oxide synthase (eNOS) protein levels and...
| Keywords: | 16:0/0:0-PC, 1-Hexadecanoyl-sn-glycero-3-Phosphatidylcholine, 1-Hexadecanoyl-sn-glycero-3-Phosphocholine,... |
| Application: | Bioactive lipid assays |
| CAS | 17364-16-8 |
| MW: | 495.6 D |
From 68.00€
*
(±)14(15)-EpETE
Item number: Cay10173-25
EDHF (endothelium-derived hyperpolarizing factor) is an unidentified mediator released from vascular endothelial cells in response to acetylcholine and bradykinin which is distinct from the NOS- (nitric oxide) and COX-derived (prostacyclin) vasodilators. Cytochrome P450 (CYP450) metabolism of polyunsaturated fatty...
| Keywords: | (±)14,15 EEQ, (±)14,15-epoxy Eicosatetraenoic Acid, (±)14,15-epoxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 131339-24-7 |
| MW: | 318.5 D |
From 72.00€
*