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4A3-SC7
Item number: Cay43989-1
4A3-SC7 is an ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA and single-guide RNA (sgRNA) in vitro and in vivo. LNPs containing 4A3-SC7 selectively accumulate in mouse liver. LNPs containing 4A3-SC7 have been used to induce gene editing in a mouse...
| Application: | Ionizable cationic lipid, LNP generation |
| CAS | 1857340-77-2 |
| MW: | 1411.07 D |
From 68.00€
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Cholic Acid (sodium salt hydrate)
Item number: Cay44008-1
Cholic acid is a primary bile acid. It is formed from cholesterol via a multistep process catalyzed by the cytochrome P450 (CYP) isoforms CYP7A1, CYP8B1, and CYP27A1. Cholic acid is conjugated to glycine or taurine by bile acid-CoA:amino acid N-acyltransferase (BAAT) to produce glycocholic acid (GCA, Cay-20276) and...
| Keywords: | CA, Cholalic Acid, Cholalin, NSC 6135, (5beta)-3alpha,7,12alpha-trihydroxy-cholan-24-oic acid, sodium salt hydrate |
| Application: | Primary bile acid |
| CAS | 206986-87-0 |
| MW: | 488.6 D |
From 38.00€
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503O8,12
Item number: Cay44137-1
503O8,12 is an ionizable cationic lipidoid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo. LNPs containing 503O8,12 and encapsulating an mRNA reporter traffic to the spleen in mice. InChI:...
| Keywords: | bis(2-octyldodecyl) 7,11-dimethyl-4,14-bis(3-((2-octyldodecyl)oxy)-3-oxopropyl)-4,7,11,14-tetraazaheptadecanedioate |
| Application: | Ionizable cationic lipidoid, LNP generation |
| CAS | 3067564-98-8 |
| MW: | 1598.73 D |
From 38.00€
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Tetradecylamine-pSar25-acetyl
Item number: Cay44163-1
Tetradecylamine-pSar25-acetyl is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of tetradecylamine. Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar physicochemical properties in vitro...
| Keywords: | C14-pSar25-acetyl, Myristylamine-pSar25-acetyl, Tetradecylamine-polysarcosine25-acetyl, Tetradecylamine-pSar25-acetyl,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 38.00€
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Tetradecylamine-PSar25-H
Item number: Cay44166-1
Tetradecylamine-PSar25-H is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of tetradecylamine. Polysarcosines (PSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing PSar exhibit similar physicochemical properties in vitro to...
| Keywords: | C14-PSar25-H, Myristylamine-PSar25, Tetradecylamine-polysarcosine25, 2-(methylamino)-N-tetradecylacetamide |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 58.00€
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N,N-ditetradecylamine-pSar50-H
Item number: Cay44167-1
N,N-ditetradecylamine-pSar50-H is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of ditetradecylamine. Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar physicochemical properties in...
| Keywords: | (C14)2-pSar50-H, Dimyristylamine-pSar50-H, N,N-ditetradecylamine-Polysarcosine50, N,N-ditetradecylamine-pSar50-H,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 88.00€
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DMPE-PGA-diol40
Item number: Cay44172-1
DMPE-PGA-diol40 is a polymer and a poly[L-glutamic acid-3-aminopropane-1,2-diol)]-conjugated form of 1,2-dimyristoyl-sn-glycero-3-PE (1,2-DMPE, Cay-15090). It can be used as a shielding lipid in the generation of lipid nanoparticles (LNPs).
| Keywords: | 1,2-Dimyristoyl-sn-glycero-3-Phosphoethanolamine-PGA-diol40,... |
| Application: | DMPE-conjugated polymer, LNP generation, shielding lipid |
From 53.00€
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Hexacosanoic Acid-d4
Item number: Cay44298-1
Hexacosanoic acid-d4 is intended for use as an internal standard for the quantification of hexacosanoic acid (Cay-13354) by GC- or LC-MS. Hexacosanoic acid is a 26-carbon saturated (26:0) very-long-chain fatty acid (VLCFA). Plasma levels of hexacosanoic acid are increased in a mouse model of adrenoleukodystrophy, a...
| Keywords: | C26:0-d4, Ceric Acid-d4, Cerotic Acid-d4, FA 26:0-d4, hexacosanoic-12,12,13,13-d4 acid |
| Application: | GC-MS, internal standard, quantification, very-long-chain fatty acid (VLCFA) |
| CAS | 1194984-85-4 |
| MW: | 400.72 D |
From 58.00€
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4A3-SC10
Item number: Cay44320-1
4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. LNPs containing 4A3-SC10 selectively accumulate in the liver, kidney, and spleen in mice. LNPs containing 4A3-SC10 and encapsulating an mRNA reporter...
| Keywords: | 4A3-SC-10 |
| Application: | Ionizable cationic lipid, LNP generation, in vitro/in vivo mRNA delivery |
| CAS | 1857340-80-7 |
| MW: | 1579.4 D |
From 68.00€
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10(S)-hydroxy Stearoyl Ethanolamide
Item number: Cay9004508-1
10(S)-hydroxy Stearoyl ethanolamide is a fatty amide. InChI: InChI=1S/C20H41NO3/c1-2-3-4-5-8-11-14-19(23)15-12-9-6-7-10-13-16-20(24)21-17-18-22/h19,22-23H,2-18H2,1H3,(H,21,24)/t19-/m0/s1 InChIKey: UUWUSZRXJDUQKH-IBGZPJMESA-N SMILES: O=C(NCCO)CCCCCCCC[C@@H](O)CCCCCCCC
| Keywords: | 10(S)-HSEA, 10(S)-hydroxy Octadecanoyl Ethanolamide, 10(S)-hydroxy Octadecanoyl-EA, 10(S)-hydroxy ODEA, 10(S)-hydroxy... |
| Application: | Fatty amide |
| MW: | 343.6 D |
From 146.00€
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Palmitic Acid (sodium salt)
Item number: Cay43561-10
Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively. Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid...
| Keywords: | C16:0, Cetylic Acid, FA 16:0, Hexadecanoic Acid, NSC 5030, hexadecanoic acid, monosodium salt |
| Application: | Long-chain saturated fatty acid, inflammation inducer |
| CAS | 408-35-5 |
| MW: | 278.41 D |
From 53.00€
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N,N-ditetradecylamine-pSar50-acetyl
Item number: Cay44164-10
N,N-ditetradecylamine-pSar50-acetyl is an amine-functionalized hydrophilic polymer and a polysarcosine-conjugated form of ditetradecylamine. Polysarcosines (pSars) have been used as alternatives to PEGylated lipids in lipid nanoparticles (LNPs). Liposomes containing pSar exhibit similar physicochemical properties in...
| Keywords: | (C14)2-pSar50-acetyl, Dimyristylamine-pSar50-acetyl, N,N-ditetradecylamine-Polysarcosine50-acetyl,... |
| Application: | Amine-functionalized hydrophilic polymer, LNP use |
From 216.00€
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