Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

Lipids are small,  organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids.... read more »
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Lipids

Lipids are small, organic molecules, that are usually hydrophobic or amphiphillic. For example, this group includes fats, fatty acids, waxes, triglycerides, sterols and phospholipids. Lipids are the main structural component of biological membranes of all cells. As such, bacterial lipid structures and glycolipids can serve as pathogen-associated molecular patterns (PAMPs) and are recognized by the human immune system. Various lipids and lipid complexes of bacterial origin are therefore used as immunostimulants.

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Linoleic Acid
Linoleic Acid

Item number: Cay90150-50

Linoleic acid is an essential omega-6 polyunsaturated fatty acid (PUFA). It is the most abundant PUFA in a variety of foods, and dietary sources of linoleic acid include vegetable oils, meats, nuts, seeds, and eggs. Linoleic acid (30 µM) increases migration of IEC-6 rat intestinal epithelial cells in a wound healing...
Keywords: 9,12-Octadecadienoic Acid, C18:2 n-6, C18:2(9Z,12Z), Telfairic Acid, 9Z,12Z-octadecadienoic acid
Application: Bioactive lipid assays
CAS 60-33-3
MW: 280.5 D
From 38.00€ *
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nor-MC3
nor-MC3

Item number: Cay43859-10

nor-MC3 is an ionizable cationic lipid that has been used in the generation of liposomal lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo and is a derivative of DLin-MC3-DMA (Cay-34364). Liposomal LNPs containing nor-MC3 at a molar ratio of 20:40:40:1.5 for nor-MC3:egg...
Keywords: (9Z,12Z)-1-(8Z,11Z)-8,11-heptade butanoic acid, 4-(dimethylamino)-cadien-1-yl-9,12-octadecadien-1-yl ester
Application: Ionizable cationic lipid, LNP generation
CAS 2870681-06-2
MW: 614.06 D
From 119.00€ *
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BSA-Palmitate Reagent Set (5 mM)
BSA-Palmitate Reagent Set (5 mM)

Item number: Cay44698-1

The BSA-Palmitate Reagent Set contains a 5 mM solution of BSA-palmitate complex and a fatty acid-free BSA control. BSA-Palmitate Complex (5 mM) is composed of palmitic acid (Cay-10006627) and fatty acid-free bovine serum albumin (BSA) at an approximately 6:1 molar ratio of palmitate:BSA. The BSA-palmitate complex...
Keywords: Bovine Serum Albumin-PA, Bovine Serum Albumin-Palmitate, BSA-PA
Application: BSA-fatty acid complex, control, cell culture
399.00€ *
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Trehalose 6,6'-dimycolate (TDM) [Cord Factor] Endotoxin-free (sterile)
Trehalose 6,6'-dimycolate (TDM) [Cord Factor]...

Item number: IAX-200-101-C100

To stimulate mouse bone marrow-derived macrophages, Cord Factor was suspended at a concentration of 0.2 mg/ml in hexane. Of the resulting solution 1 or 10 µg/well were layered in 96-well tissue culture plates and the solvent completely evaporated. Control wells were layered with solvent without Cord Factor and also...
Keywords: TDM, CF
Application: Mycobacterial glycolipid
CAS 61512-20-7
334.00€ *
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Ganglioside GM1 . sodium salt (bovine brain)
Ganglioside GM1 . sodium salt (bovine brain)

Item number: AG-CN2-9000-M001

Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...
Keywords: GM1 . Na, Monosialoganglioside GM1 . Na
Application: Acidic glycosphingolipid
CAS 37758-47-7
MW: 1545,8 D
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1,2,3-Triheptadecanoyl Glycerol
1,2,3-Triheptadecanoyl Glycerol

Item number: Cay16489-1

1,2,3-Triheptadecanoyl glycerol is a triacylglycerol that contains heptadecanoic acid (Cay-19722) at the sn-1, sn-2, and sn-3 positions.Formal Name: heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester. CAS Number: 2438-40-6. Synonyms: Glycerol Triheptadecanoate, TG(17:0/17:0/17:0). Molecular Formula: C54H104O6....
Keywords: Glycerol Triheptadecanoate, TG(17:0/17:0/17:0), heptadecanoic acid, 1,1',1''-(1,2,3-propanetriyl) ester
Application: Saturated triacylglycerol
CAS 2438-40-6
MW: 849.4 D
From 53.00€ *
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Prostaglandin J2
Prostaglandin J2

Item number: Cay18500-500

Prostaglandin J2 (PGJ2) is a metabolite of PGD2 (Cay-12010) and an agonist of the prostaglandin D2 (PGD2) receptor subtypes DP1 and DP2/CRTH. It is formed from PGD2 by spontaneous dehydration. PGJ2 binds to DP1 and DP2/CRTH receptors (Kis = 0.9 and 6.6 nM, respectively) and either increases or inhibits the...
Keywords: PGJ2, 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid
Application: Bioactive lipid assays
CAS 60203-57-8
MW: 334.5 D
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tetranor-PGEM
tetranor-PGEM

Item number: Cay14840-25

tetranor-Prostaglandin E metabolite (tetranor-PGEM) is the major urinary metabolite of PGE2 (Cay-14010). Urine levels of tetranor-PGEM are increased in patients with diabetic nephropathy. Increased urine levels are also associated with a higher risk of breast cancer in postmenopausal women with a body mass index...
Keywords: tetranor-Prostaglandin E Metabolite, 9,15-dioxo-11alpha-hydroxy-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid
Application: Bioactive lipid assays
CAS 24769-56-0
MW: 328.4 D
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2-Arachidonoyl Glycerol-d8
2-Arachidonoyl Glycerol-d8

Item number: Cay362160-100

2-Arachidonoyl glycerol-d8 (2-AG-d8) is intended for use as an internal standard for the quantification of 2-AG (Cay-62160) by GC- or LC-MS. 2-AG is an endogenous agonist of the CB1 receptor. Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system, it is the most abundant molecular...
Keywords: 2-AG-d8, 5Z,8Z,11Z,14Z-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid, 2-glyceryl ester
Application: Standard
CAS 924894-97-3
MW: 386.6 D
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1-Arachidonoyl Glycerol
1-Arachidonoyl Glycerol

Item number: Cay62150-1

The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. However, 2-AG is chemically unstable and undergoes rapid...
Keywords: 1-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 1-glyceryl ester
Application: CB1 receptor agonist
CAS 35474-99-8
MW: 378.6 D
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C14-4
C14-4

Item number: Cay38942-10

C14-4 is an ionizable cationic lipid (pKa = 6.5). It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing C14-4 and encapsulating mRNA encoding chimeric antigen receptor (CAR) induce CAR expression in primary human T cells ex vivo to the same level as expression...
Keywords: C14-494, Lipid B4,...
Application: Ionizable cationic lipid, LNP formation
CAS 2639634-80-1
MW: 1365.3 D
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Xestospongin C
Xestospongin C

Item number: Cay64950-10

Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction...
Keywords: Araguspongine E, XeC,...
Application: Bioactive lipid assays
CAS 88903-69-9
MW: 446.7 D
From 162.00€ *
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