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13(S)-HODE-d4
Item number: Cay338610-25
13(S)-HODE-d4 is intended for use as an internal standard for the quantification of 13-HODE by GC- or LC-MS. (±)-13-HODE is formed via non-enzymatic oxidation of linoleic acid (Cay-90150, Cay-90150.1, Cay-21909). 13(S)-HODE and 13(R)-HODE are formed by lipoxygenase- and cyclooxygenase-mediated oxidation of linoleic...
| Keywords: | 13S-hydroxy-9Z,11E-octadecadienoic-9,10,12,13-d4 acid |
| Application: | Standard |
| CAS | 139408-39-2 |
| MW: | 300.5 D |
From 201.00€
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10(S),17(S)-DiHDHA
Item number: Cay10008128-25
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase...
| Keywords: | 10(S),17(S)-DiHDoHE, PDX, Protectin DX, 10(S),17(S)-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 871826-47-0 |
| MW: | 360.5 D |
From 271.00€
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Leukotriene E4
Item number: Cay20410-25
Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
| Keywords: | LTE4, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 75715-89-8 |
| MW: | 439.6 D |
From 221.00€
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5(S)-HETE
Item number: Cay34230-25
5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.Formal Name:...
| Keywords: | 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 70608-72-9 |
| MW: | 320.5 D |
From 169.00€
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2-Arachidonoyl Glycerol-d5
Item number: Cay362162-100
2-Arachidonoyl glycerol-d5 (2-AG-d5) is intended for use as an internal standard for the quantification of 2-AG (Cay-62160) by GC- or LC-MS. 2-AG is an endogenous agonist of the CB1 receptor. Unlike anandamide, 2-AG is present at relatively high levels in the central nervous system, it is the most abundant molecular...
| Keywords: | 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester |
| Application: | Standard |
| CAS | 2522598-88-3 |
| MW: | 383.6 D |
From 142.00€
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(±)17-HDHA
Item number: Cay33650-25
(±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA, Cay-90310) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA (Cay-10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of...
| Keywords: | (±)17-HDoHE, 17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-hydroxy-4Z,7Z,10Z,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Oxidative stress marker |
| CAS | 90780-52-2 |
| MW: | 344.5 D |
From 112.00€
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15(S)-HETE
Item number: Cay34720-25
15(S)-HETE is an active metabolite of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607). It is formed via oxidation of arachidonic acid by 15-lipoxygenase 2 (15-LO-2) in macrophages, as well as the prostate, lung, and skin, but also by 15-LO-1 in airway epithelial cells, eosinophils, and reticulocytes....
| Keywords: | 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 54845-95-3 |
| MW: | 320.5 D |
From 68.00€
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Palmitoleic Acid
Item number: Cay10009871-100
Palmitoleic acid is an omega-7 monounsaturated fatty acid that has been found in macadamia and sea buckthorn oils. It increases basal and insulin-stimulated glucose uptake and glucose transporter 4 (Glut4) protein levels in 3T3-L1 adipocytes when used at a concentration of 200 µM. Ex vivo, palmitoleic acid (300...
| Keywords: | (9Z)-Hexadecenoic Acid, cis-Palmitoleic Acid, C16:1 n-7, C16:1(9Z), (9Z)-hexadecenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 373-49-9 |
| MW: | 254.4 D |
From 49.00€
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JTE-013
Item number: Cay10009458-10
JTE-013 is a sphingosine-1-phosphate receptor 2 (S1P2) and S1P4 antagonist (IC50s = 17 and 237 nM, respectively). It is selective for S1P2 over S1P1 and S1P3 (IC50s = >10 µM for both). JTE-013 (1 and 10 µM) reverses S1P-induced inhibition of human umbilical vein endothelial cell (HUVEC) and smooth muscle cell (SMC)...
| Keywords: | N-(2,6-dichloro-4-pyridinyl)-2-[1,3-dimethyl-4-(1-methylethyl)-1H-pyrazolo[3,4-b]pyridin-6-yl]-hydrazinecarboxamide |
| Application: | S1P2 receptor antagonist |
| CAS | 383150-41-2 |
| MW: | 408.3 D |
From 40.00€
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Pentacosanoic Acid methyl ester
Item number: Cay10006451-100
Long chain saturated fatty acids and their esters are common components of plant lipids. Pentacosanoic acid methyl ester is the methyl ester of the 25-carbon, fully saturated fatty acid pentacosanoic acid. This product is designed to be used as a standard in total fatty acid analysis.Formal Name: pentacosanoic acid,...
| Keywords: | Methyl Pentacosanoate, pentacosanoic acid, methyl ester |
| Application: | Standard |
| CAS | 55373-89-2 |
| MW: | 396.7 D |
From 99.00€
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(±)17(18)-EpETE
Item number: Cay50861-500
(±)17(18)-EpETE is biosynthesized by the stereospecific epoxidation of the omega-3 bond of EPA. (±)17(18)-EpETE at 100 nM was found to be a potent and selective activator of large-conductance calcium-activated potassium channels (KCa1.1/BK) in vascular smooth muscle cells. It is possible that some of the physiologic...
| Keywords: | (±)17,18-EEQ, (±)17,18-epoxy Eicosatetraenoic Acid, (±)17,18-epoxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Application: | Bioactive lipid assays |
| MW: | 318.5 D |
From 93.00€
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Palmitic Acid Alkyne
Item number: Cay13266-1
Protein S-palmitoylation is the post-translational acylation of proteins and serves to regulate localization, stability, and interaction with associates and substrates. Palmitic acid alkyne is a form of palmitic acid (Cay-10006627) with an omega-terminal alkyne. The terminal alkyne group can be used in linking...
| Keywords: | Alk-14, Click Tag(TM) Palmitic Acid Alkyne, 15-hexadecynoic acid |
| Application: | Lipid bioconjugation |
| CAS | 99208-90-9 |
| MW: | 252.4 D |
From 95.00€
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