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(+)-Etomoxir
Item number: Cay9004470-10
(+)-Etomoxir is an inhibitor of carnitine palmitoyltransferase 1 (CPT1) and a prodrug form of (+)-etomoxir (Cay-11969). It is an ethyl ester that is cleaved by intracellular esterases to release the active inhibitor of CPT1. (+)-Etomoxir decreases palmitate (Cay-10010279) oxidation and increases glucose oxidation in...
| Keywords: | (R)-(+)-Etomoxir, (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylic acid, ethyl ester |
| Application: | Carnitine palmitoyltransferase 1 (CPT1) inhibitor prodrug |
| CAS | 124083-20-1 |
| MW: | 326.81 D |
From 117.00€
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Pinolenic Acid ethyl ester (technical grade)
Item number: Cay9004488-100
Pinolenic acid ethyl ester is a polyunsaturated fatty acid ethyl ester. Oral administration of pinolenic acid ethyl ester (100 mg/kg) decreases blood glucose levels in an oral glucose tolerance test in mice.
| Keywords: | all-cis-5,9,12-Octadecatrienoic Acid ethyl ester, all-Z-5,9,12-Octadecatrienoic Acid ethyl ester, C18:3 (cis-5,9,12) ethyl... |
| Application: | Polyunsaturated fatty acid ethyl ester |
| CAS | 493015-74-0 |
| MW: | 306.5 D |
From 172.00€
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8-iso-15-keto Prostaglandin F2alpha
Item number: Cay16390-100
8-iso-15-keto Prostaglandin F2alpha (8-iso-15-keto PGF2alpha) is a metabolite of the isoprostane 8-iso PGF2alpha in rabbits, monkeys, and humans. 8-isoprostane (8-iso PGF2alpha) is a prostaglandin-like product of non-specific lipid peroxidation. In both humans and monkeys, exogenously infused 8-iso PGF2alpha is...
| Keywords: | 8-epi-15-keto PGF2alpha, 8-iso-15-keto PGF2alpha, 9alpha,11alpha-dihydroxy-15-oxo-(8beta)-prosta-5Z,13E-dien-1-oic acid |
| Application: | 8-iso PGF2alpha metabolite, vasoconstrictor |
| CAS | 191919-01-4 |
| MW: | 352.5 D |
From 44.00€
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PAF C-16
Item number: Cay60900-5
PAF C-16 is a naturally occurring phospholipid produced upon stimulation through two distinct pathways known as the "remodeling" and 'de novo' pathways. It is a potent mediator of neutrophil migration, and the production of reactive oxygen species, and IL-6 in human macrophages. It is a more potent mediator of...
| Keywords: | Platelet-activating Factor C-16, 1-O-hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine |
| Application: | Bioactive lipid assays |
| CAS | 74389-68-7 |
| MW: | 523.7 D |
From 49.00€
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15(S)-HETE-d8
Item number: Cay334720-25
15(S)-HETE-d8 is intended for use as an internal standard for the quantification of 15(S)-HETE (Cay-34720) by GC- or LC-MS. (±)15-HETE and 15(S)-HETE are formed via non-enzymatic and 15-lipoxygenase-mediated oxidation of arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607), respectively. 15(R)-HETE is formed by...
| Keywords: | 15(S)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic-5,6,8,9,11,12,14,15-d8 acid |
| Application: | Standard |
| CAS | 84807-87-4 |
| MW: | 328.5 D |
From 243.00€
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25-hydroxy Cholesterol
Item number: Cay11097-5
25-hydroxy Cholesterol is an oxysterol. It is formed from cholesterol by cholesterol-25-hydroxylase, and its production can be induced by inflammation or infection. 25-hydroxy Cholesterol suppresses endogenous cholesterol synthesis by binding to insulin-induced gene (INSIG) proteins and preventing sterol regulatory...
| Keywords: | 25-OH Cholesterol, cholest-5-ene-3beta,25-diol |
| Application: | Metabolic studies |
| CAS | 2140-46-7 |
| MW: | 402.7 D |
From 35.00€
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16,16-dimethyl Prostaglandin E2
Item number: Cay14750-1
16,16-dimethyl PGE2 is a competitive inhibitor of 15-hydroxy PGDH, but it is not a substrate for the enzyme. Because of its resistance to metabolism by 15-hydroxy PGDH, it has a prolonged half-life in vivo. 16,16-dimethyl PGE2 acts as an agonist on most EP receptor subtypes, and has been used experimentally to...
| Keywords: | 16,16-dimethyl PGE2, 9-oxo-11alpha,15R-dihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid |
| Application: | PGDH inhibitor |
| CAS | 39746-25-3 |
| MW: | 380.5 D |
From 117.00€
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(±)13-HODE
Item number: Cay38600-100
(±)13-HODE is one of the two racemic monohydroxy fatty acids resulting from the non-enzymatic oxidation of linoleic acid. It is the principle hydroxylated fatty acid in human psoriatic skin scales, with a mean concentration of 17 ng/mg.Formal Name: (±)-13-hydroxy-9Z,11E-octadecadienoic acid. CAS Number: 18104-45-5....
| Keywords: | (±)-13-hydroxy-9Z,11E-octadecadienoic acid |
| Application: | Bioactive lipid studies |
| CAS | 18104-45-5 |
| MW: | 296.4 D |
From 197.00€
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13-Docosenamide
Item number: Cay90377-1
13-Docosenamide is the amide of docosenoic acid. It was first identified in the cerebrospinal fluid of sleep-deprived cats. It has also been detected in the cerebrospinal fluid of rats and humans. 13-Docosenamide causes reduced mobility and slightly lessened awareness in rats, whereas 9-octadecenamide induces...
| Keywords: | cis-13-Docosenamide, Armoslip E, Erucamide, 13Z-docosenamide |
| Application: | Cerebrospinal fluid constituent |
| CAS | 112-84-5 |
| MW: | 337.6 D |
From 35.00€
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Palmitoyl Ethanolamide
Item number: Cay90350-5
Palmitoyl ethanolamide (PEA) is an endogenous fatty N-acyl ethanolamine and a derivative of the endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050). It selectively activates peroxisome proliferator-activated receptor alpha (PPARalpha, EC50 = 3.1 µM) over PPARbeta/delta and PPARgamma in HeLa cells expressing...
| Keywords: | Palmidrol, PEA, N-(2-hydroxyethyl)-hexadecanamide |
| Application: | Bioactive lipid assays |
| CAS | 544-31-0 |
| MW: | 299.5 D |
From 44.00€
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SQ 29,548
Item number: Cay19025-1
SQ 29,548 is a highly selective TP receptor antagonist which binds to the human recombinant TP receptor with a Ki of 4.1 nM. It inhibits the aggregation of washed human platelets induced by U-46619 with an IC50 of 0.06 µM. It antagonizes U-46619 induced contraction of rat and guinea pig tracheal, arterial, and...
| Keywords: | [1S-[1alpha,2alpha(Z),3alpha,4alpha]]-7-[3-[[2-[(phenylamino)carbonyl]hydrazino]methyl]-7-oxabicyclo[2.2.1]hept-2-yl]-5-he... |
| Application: | TP receptor antagonist |
| CAS | 98672-91-4 |
| MW: | 387.5 D |
From 116.00€
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10(S),17(S)-DiHDHA
Item number: Cay10008128-25
Protectin D1 (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities. 10(S),17(S)-DiHDHA is a DHA metabolite, also referred to as protectin DX (PDX). It is produced by an apparent double lipoxygenase...
| Keywords: | 10(S),17(S)-DiHDoHE, PDX, Protectin DX, 10(S),17(S)-dihydroxy-4Z,7Z,11E,13Z,15E,19Z-docosahexaenoic acid |
| Application: | Bioactive lipid assays |
| CAS | 871826-47-0 |
| MW: | 360.5 D |
From 249.00€
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