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Product information "17-phenyl trinor Prostaglandin F2alpha methyl amide"
17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) is a metabolically stable analog of PGF2alpha and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2alpha. The ethyl amide of 17-phenyl trinor PGF2alpha bimatoprost has been approved for use as an ocular hypotensive drug. 17-phenyl trinor Prostaglandin F2alpha (17-phenyl trinor PGF2alpha) is a metabolically stable analog of PGF2alpha and is a potent agonist for the FP receptor, binding with a relative potency of 756% compared to that of PGF2alpha. 17-phenyl trinor PGF2alpha methyl amide is an analog of bimatoprost.Formal Name: (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-N-methyl-5-heptenamide. CAS Number: 155206-01-2. Synonyms: Bimatoprost methyl amide, Methylamido Dihydro Noralfaprostal, 17-phenyl trinor PGF2alpha methyl amide. Molecular Formula: C24H35NO4. Formula Weight: 401.5. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Acetonitrile: 3 mg/ml, DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 50 mg/ml, PBS (pH 7.2): 300 µg/ml. SMILES: O[C@@H]1[C@H](C/C=C\CCCC(NC)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1. InChi Code: InChI=1S/C24H35NO4/c1-25-24(29)12-8-3-2-7-11-20-21(23(28)17-22(20)27)16-15-19(26)14-13-18-9-5-4-6-10-18/h2,4-7,9-10,15-16,19-23,26-28H,3,8,11-14,17H2,1H3,(H,25,29)/b7-2-,16-15+/t19-,20+,21+,22-,23+/m0/s1. InChi Key: UWIWNJFBNIMMGY-FDBOBMRISA-N.
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