1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid (Cay-10011298) at the sn-1 position and 15(S)-HpETE (Cay-44720) at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC (SAPC, Cay-10009864) by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 µM.Formal Name: (7R,13Z,16Z,19Z,21E,23S)-23-hydroperoxy-4-hydroxy-N,N,N-trimethyl-9-oxo-7-[[(1-oxooctadecyl)oxy]methyl]-3,5,8-trioxa-4-phosphaoctacosa-13,16,19,21-tetraen-1-aminium, inner salt, 4-oxide. CAS Number: 154436-48-3. Synonyms: 15(S)-HpETE-SAPC, 15(S)-Hydroperoxyeicostetraenoic Acid-SAPC, 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-Phosphatidylcholine. Molecular Formula: C46H84NO10P. Formula Weight: 842.1. Purity: >98%. Formulation: (Request formulation change), A solution in ethanol. Solubility: Ethanol: 30 mg/mL, Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL. lambdamax: 234 nm. SMILES: O=C(CCCCCCCCCCCCCCCCC)OC[C@@H](OC(CCC/C=C\C/C=C\C/C=C\C=C\[C@@H](OO)CCCCC)=O)COP(OCC[N+](C)(C)C)([O-])=O. InChi Code: InChI=1S/C46H84NO10P/c1-6-8-10-11-12-13-14-15-16-17-20-23-26-29-33-37-45(48)53-41-44(42-55-58(51,52)54-40-39-47(3,4)5)56-46(49)38-34-30-27-24-21-18-19-22-25-28-32-36-43(57-50)35-31-9-7-2/h18-19,24-25,27-28,32,36,43-44H,6-17,20-23,26,29-31,33-35,37-42H2,1-5H3,(H-,50,51,52)/b19-18-,27-24-,28-25-,36-32+/t43?,44-/m1/s1. InChi Key: VZVJELKWXFHACO-XVQSNERZSA-N. Side Chain Carbon Sum: 38:4.