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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| Cay43425-1 | 1 mg | - |
6 - 10 business days* |
518.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Zofenopril-d5 is intended for use as an internal standard for the quantification of zofenopril... more
Product information "Zofenopril-d5"
Zofenopril-d5 is intended for use as an internal standard for the quantification of zofenopril (Cay-29525) by GC- or LC-MS. Zofenopril is a prodrug form of the angiotensin-converting enzyme (ACE) inhibitor zofenoprilat (Cay-38124). Zofenopril is hydrolyzed by cardiac esterases in vivo to form zofenoprilat. It inhibits ACE with an IC50 value of 0. nM in heart tissue homogenates and inhibits cardiac ACE activity in isolated perfused rat hearts. It reduces mean arterial blood pressure in two kidney-one clip renal hypertensive (2K-1C) rats and spontaneously hypertensive rats (SHRs) when administered at doses of 2. 6. and 22 mg/kg. Unlike the ACE inhibitor ramipril (Cay-15558), zofenopril does not affect bronchoalveolar lavage fluid (BALF) levels of bradykinin or prostaglandin E2 (PGE2, Cay-14010) or increase coughing induced by citric acid in guinea pigs.. Solulibility: DMSO: soluble: Methanol: soluble.
| Keywords: | (4S)-1-[(2S)-3-(benzoylthio)-2-methyl-1-oxopropyl]-4-((phenyl-d5)thio)-L-proline |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43425 |
Properties
| Application: | GC-MS, LC-MS, internal standard, ACE inhibitor |
| MW: | 434.58 D |
| Formula: | C22H18D5NO4S2 |
| Purity: | >99% deuterated forms (d1-d5) |
| Format: | Solid |
Database Information
| KEGG ID : | K01283 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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