YE 120

YE 120
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay29720-1 1 mg -

6 - 10 business days*

85.00€
Cay29720-5 5 mg -

6 - 10 business days*

246.00€
 
YE 120 is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50 value of 32 nM in a... more
Product information "YE 120"
YE 120 is an agonist of G protein-coupled receptor 35 (GPR35) with an EC50 value of 32 nM in a dynamic mass redistribution (DMR) assay using HT-29 cells. It induces beta-arrestin translocation in Tango GPR35-bla U2OS cells (EC50 = 10.2 µM). YE 120 (10 µM) promotes wound closure in YAMC colonic epithelial and IEC-6 intestinal epithelial cell monolayers, an effect that can be blocked by the GPR35 antagonist CID-2745687 (Cay-12046).Formal Name: 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile. CAS Number: 383124-82-1. Molecular Formula: C16H9Cl2N3O. Formula Weight: 330.2. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM. SMILES: CC1=C(C#N)/C(OC1(C)C2=CC(Cl)=C(Cl)C=C2)=C(C#N)/C#N. InChi Code: InChI=1S/C16H9Cl2N3O/c1-9-12(8-21)15(10(6-19)7-20)22-16(9,2)11-3-4-13(17)14(18)5-11/h3-5H,1-2H3. InChi Key: RSWZFAPYKOARNG-UHFFFAOYSA-N.
Keywords: 2-[3-cyano-5-(3,4-dichlorophenyl)-4,5-dimethyl-2(5H)-furanylidene]-propanedinitrile
Supplier: Cayman Chemical
Supplier-Nr: 29720

Properties

Application: GPR35 agonist
MW: 330.2 D
Formula: C16H9Cl2N3O
Purity: >98%
Format: Solid

Database Information

CAS : 383124-82-1| Matching products
KEGG ID : K04276 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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