Y16
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
An inhibitor of the Rho GEF 12-RhoA protein-protein interaction, binds to the DH-PH domain of Rho... more
Product information "Y16"
An inhibitor of the Rho GEF 12-RhoA protein-protein interaction, binds to the DH-PH domain of Rho GEF 12 in a cell-free assay (Kd = 76 nM), inhibits serum-induced phosphorylation of MLC and FAK, a marker of RhoA activity, in NIH3T3 cells at 10 and 30 µM, inhibits cell growth, migration, invasion, and mammosphere formation in MCF-7 breast cancer cells from 5-30 µM. Formulation: A solid. InChI: InChI=1S/C24H20N2O3/c1-17-7-5-9-19(13-17)16-29-21-12-6-8-18(14-21)15-22-23(27)25-26(24(22)28)20-10-3-2-4-11-20/h2-15H,16H2,1H3,(H,25,27). InChIKey: ITMLWGWTDWJSRZ-UHFFFAOYSA-N. SMILES: O=C1NN(C(C1=CC2=CC(OCC3=CC(C)=CC=C3)=CC=C2)=O)C4=CC=CC=C4
| Keywords: | 4-[[3-[(3-methylphenyl)methoxy]phenyl]methylene]-1-phenyl-3,5-pyrazolidinedione |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 42399 |
Properties
| Application: | Rho GEF 12-RhoA protein-protein interaction inhibitor |
| Immunogen: | 384.43 |
| MW: | 384.43 D |
| Formula: | C24H20N2O3 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 429653-73-6| Matching products |
| KEGG ID : | K07532 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
|
| H Phrases: | H400, H410 |
| P Phrases: | P273, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed