Werner Syndrome RecQ Helicase-IN-4

Item number	Size	Manual	SDS	Delivery time	Price
Cay41679-5	5 mg	-	-	5 - 10 business days*	610.00€
Cay41679-10	10 mg	-	-	5 - 10 business days*	855.00€
Cay41679-25	25 mg	-	-	5 - 10 business days*	1,509.00€
Cay41679-50	50 mg	-	-	5 - 10 business days*	2,743.00€

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An inhibitor of WRN (IC50 = 60 nM), selectively inhibits the growth of SW48 cells over... more

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Product information "Werner Syndrome RecQ Helicase-IN-4"

An inhibitor of WRN (IC50 = 60 nM), selectively inhibits the growth of SW48 cells over DLD-1-WRN-KO cells (GI50s = 70 and >10,000 nM, respectively), reduces tumor volume in an SW48 mouse xenograft model at 240 mg/kg per day. Formulation: A solid. InChI: InChI=1S/C32H33F3N8O5/c1-3-23-27(40-11-13-41(14-12-40)29(46)26-24(44)5-4-10-36-26)30(47)43-31(38-28(39-43)20-8-15-48-16-9-20)42(23)18-25(45)37-22-7-6-21(17-19(22)2)32(33,34)35/h4-8,10,17,44H,3,9,11-16,18H2,1-2H3,(H,37,45). InChIKey: FLRLAYBOOSONEK-UHFFFAOYSA-N. SMILES: CC1=CC(C(F)(F)F)=CC=C1NC(CN(C2=NC(C3=CCOCC3)=NN24)C(CC)=C(N5CCN(C(C6=C(C=CC=N6)O)=O)CC5)C4=O)=O

Keywords:	Werner Syndrome RecQ Helicase Inhibitor 4, WS RecQ Helicase Inhibitor 4, WS RecQ Helicase-IN-4, 2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(3-hydroxy-2-pyridinyl)carbonyl]-1-piperazinyl]-N-[2-methyl-4-(trifluoromethyl)phenyl]-7-oxo-[1,2,4]triazolo[1,5-a]
Supplier:	Cayman Chemical
Supplier-Nr:	41679

Properties

Application:	WRN inhibitor
Immunogen:	666.7
MW:	666.7 D
Formula:	C32H33F3N8O5
Purity:	>95%
Format:	Solid

Database Information

CAS :	2869954-53-8\| Matching products
KEGG ID :	K10900 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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