Vadimezan
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an... more
Product information "Vadimezan"
Description: Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without affecting blood flow in normal tissues. Target: Influenza Virus, IFNAR, VDA, STING. Smiles: Cc1ccc2c(oc3c(CC(O)=O)cccc3c2=O)c1C. References: Cai Y, et al. Activation of STING by SAMHD1 Deficiency Promotes PANoptosis and Enhances Efficacy of PD-L1 Blockade in Diffuse Large B-cell Lymphoma. Int J Biol Sci. 2023 Aug 28,19(14):4627-4643.
| Keywords: | ASA-404, NSC 640488, 5,6-Dimethylxanthenone-4-acetic Acid, DMXAA |
| Supplier: | TargetMol |
| Supplier-Nr: | T6273 |
Properties
| Application: | VEGFR2 inhibitor, apoptosis inducer |
| MW: | 282.29 D |
| Formula: | C17H14O4 |
Database Information
| CAS : | 117570-53-3| Matching products |
| KEGG ID : | K05098 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H302, H400 |
| P Phrases: | P264, P270, P273, P301+310, P330, P391, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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