Trametinib (DMSO solvate)
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a highly potent and... more
Product information "Trametinib (DMSO solvate)"
Description: Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a highly potent and selective MEK inhibitor that specifically inhibits MEK1/2 (IC50: 2 nM). Target: Apoptosis, MEK. Smiles: CS(C)=O.CC(=O)Nc1cccc(c1)-n1c2c(C)c(=O)n(C)c(Nc3ccc(I)cc3F)c2c(=O)n(C2CC2)c1=O. References: Abe H , Kikuchi S , Hayakawa K , et al. Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate)[J]. ACS MEDICINAL CHEMISTRY LETTERS, 2011, 2(4):320-324.
| Keywords: | Trametinib DMSO solvate, GSK-1120212 (DMSO solvate), JTP-74057 (DMSO solvate), Trametinib dimethyl sulfoxide |
| Supplier: | TargetMol |
| Supplier-Nr: | T5857 |
Properties
| Application: | Targets mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] (MAP2K1, MEK1) |
| MW: | 693.53 D |
| Formula: | C28H29FIN5O5S |
Database Information
| CAS : | 1187431-43-1| Matching products |
| KEGG ID : | K04368 | Matching products |
| Protein Atlas Nr. : | Phosphorylation (other) |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H317, H361, H372, H410 |
| P Phrases: | P201, P202, P260, P261, P264, P270, P272, P273, P280, P314, P321, P391, P302+P352, P308+P313, P333+P313, P362+P364, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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