Tozasertib

Item number	Size	Delivery time	Price
TGM-T2509-1mL	1 ml	7 - 10 business days*	48.00€
TGM-T2509-50mg	50 mg	7 - 10 business days*	58.00€
TGM-T2509-100mg	100 mg	7 - 10 business days*	95.00€

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Description: Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora... more

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Product information "Tozasertib"

Description: Tozasertib (MK-0457) is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C). It shows selectivity against more than 190 different kinases. Target: Aurora Kinase, Autophagy. Smiles: CN1CCN(CC1)c1cc(Nc2cc(C)[nH]n2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1. References: Harrington EA, et al. VX-680, a potent and selective smallmolecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo. Nat Med. 2004, 10:262-7.

Keywords:	MK-0457, VX 680
Supplier:	TargetMol
Supplier-Nr:	T2509

Properties

Application:	Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1)
MW:	464.59 D
Formula:	C23H28N8OS
Format:	32160405

Database Information

CAS :	639089-54-6\| Matching products
KEGG ID :	K05092 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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