Tovinontrine

Item number	Size	Delivery time	Price
TGM-T61833-1mg	1 mg	7 - 10 business days*	105.00€
TGM-T61833-5mg	5 mg	7 - 10 business days*	261.00€
TGM-T61833-1mL	1 ml	7 - 10 business days*	287.00€
TGM-T61833-10mg	10 mg	7 - 10 business days*	376.00€
TGM-T61833-25mg	25 mg	7 - 10 business days*	611.00€
TGM-T61833-50mg	50 mg	7 - 10 business days*	817.00€

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Description: Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of... more

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Product information "Tovinontrine"

Description: Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment. It exhibits high efficacy, with IC 50 values of 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively [1]. Target: PDE. Smiles: C[C@@H]1CN(Cc2ncccn2)C[C@H]1c1cn2c(ncc2c(=O)[nH]1)C1CCOCC1. References: McArthur JG, et al. A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease. Haematologica. 2020,105(3):623-631.

Keywords:	IMR-687
Supplier:	TargetMol
Supplier-Nr:	T61833

Properties

Application:	Targets high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] (PDE9)
MW:	394.47 D
Formula:	C21H26N6O2
Format:	32160405

Database Information

CAS :	2062661-53-2\| Matching products
KEGG ID :	K13761 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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