TNF-alpha-IN-2

Item number	Size	Manual	Delivery time	Price
Cay45397-5	5 mg	-	6 - 10 business days*	1,068.00€
Cay45397-10	10 mg	-	6 - 10 business days*	1,496.00€
Cay45397-25	25 mg	-	6 - 10 business days*	2,670.00€
Cay45397-50	50 mg	-	6 - 10 business days*	3,738.00€

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An inhibitor of TNF-alpha, inhibits TNF-alpha-induced secretion of a SEAP reporter in HEK-Blue... more

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Product information "TNF-alpha-IN-2"

An inhibitor of TNF-alpha, inhibits TNF-alpha-induced secretion of a SEAP reporter in HEK-Blue cells (IC50 = 27 nM), reduces paw TNF-alpha, IL-1beta, and IL-6 levels and swelling in a mouse model of alpha-collagen antibody-induced arthritis. SMILES: C[C@H](C1=CC(C#N)=CC=C1F)NC2=C(Cl)C(C)=NC3=C2N=C(C4=CN=C(C(C)(O)C)N=C4)C(F)=C3. InChi Code: InChI=1S/C25H21ClF2N6O/c1-12(16-7-14(9-29)5-6-17(16)27)33-23-20(26)13(2)32-19-8-18(28)21(34-22(19)23)15-10-30-24(31-11-15)25(3,4)35/h5-8,10-12,35H,1-4H3,(H,32,33)/t12-/m1/s1. InChi Key: UDLNDXDUOBMZIQ-GFCCVEGCSA-N

Keywords:	TNF-Inhibitor 2, 3-[(1R)-1-[[3-chloro-7-fluoro-6-[2-(1-hydroxy-1-methylethyl)-5-pyrimidinyl]-2-methyl-1,5-naphthyridin-4-yl]amino]ethyl]-4-fluoro-benzonitrile
Supplier:	Cayman Chemical
Supplier-Nr:	45397

Properties

Application:	TNF-alpha inhibitor
MW:	494.93 D
Formula:	C25H21ClF2N6O
Purity:	>98%
Format:	Solid

Database Information

CAS :	2074702-04-6\| Matching products
KEGG ID :	K03156 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	-20°C (International: -20°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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