Thalidomide-O-amido-C4-NH2

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Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
TGM-T17818-100mg	100 mg				7 - 10 business days*		-
TGM-T17818-500mg	500 mg				7 - 10 business days*		-

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Description: Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized... more

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Product information "Thalidomide-O-amido-C4-NH2"

Description: Thalidomide-O-amido-C4-NH2 (Cereblon Ligand-Linker Conjugates 6) is a synthesized compound combining a Thalidomide-based cereblon ligand with a linker, serving as an E3 ligase ligand-linker conjugate for the synthesis of PROTACs[1]. Target: Others. Smiles: O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2OCC(NCCCCN)=O. References: Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression.J Med Chem. 2018 Jan 25,61(2):462-481.

Keywords:	Cereblon Ligand-Linker Conjugates 6, E3 Ligase Ligand-Linker Conjugates 19
Supplier:	TargetMol
Supplier-Nr:	T17818

Properties

Application:	Protac(R) reagent
MW:	402.4 D
Formula:	C19H22N4O6

Database Information

CAS :	1799711-24-2\| Matching products
KEGG ID :	K11793 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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