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Description: TH-257 is a Potent and selective allosteric LIMK 1/2 inhibitor(LIMK1 and LIMK2, IC50 of 84 nM and 39 nM). Target: LIM Kinase. Smiles: CCCCN(Cc1ccccc1)C(=O)c1ccc(cc1)S(=O)(=O)Nc1ccccc1. References: Fabrizio M . Recent advances in the rational design and development of LIM kinase inhibitors are not enough to enter clinical trials[J]. European Journal of Medicinal Chemistry, 2018:S0223523418305075-.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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