Tesaglitazar
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: Tesaglitazar is a potent and selective peroxide PPARalpha / gamma receptor dual... more
Product information "Tesaglitazar"
Description: Tesaglitazar is a potent and selective peroxide PPARalpha / gamma receptor dual agonist with a more potent affinity for PPARgamma than PPARalpha, The EC50 values for rat PPARalpha and human PPARalpha were 13.4 µM and 3.6 µM, respectively, and 0.2 µM for rat PPARgamma and human PPARgamma. Tesaglitazar induced DNA synthesis and fibrosarcoma formation in rat subcutaneous mesenchymal cells. Target: PPAR. Smiles: CCO[C@@H](Cc1ccc(OCCc2ccc(OS(C)(=O)=O)cc2)cc1)C(O)=O. References: Zhang BC, et al. Tesaglitazar ameliorates non-alcoholic fatty liver disease and atherosclerosis development in diabetic low-density lipoprotein receptor-deficient mice. Exp Ther Med. 2012,4(6):987-992.
| Supplier: | TargetMol |
| Supplier-Nr: | T17044 |
Properties
| Application: | Targets peroxisome proliferator-activated receptor alpha (NR1C1, PPARA) |
| MW: | 408.47 D |
| Formula: | C20H24O7S |
Database Information
| CAS : | 251565-85-2| Matching products |
| KEGG ID : | K07294 | Matching products |
| Protein Atlas Nr. : | Gene Regulation |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +4°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | H315, H319, H335 |
| P Phrases: | P261, P264, P271, P280, P312, P321, P302+P352, P304+P340, P305+P351+P338, P332+P313, P337+P313, P362+P364, P405, P403+P233, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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