TC-I 2000

TC-I 2000 is an antagonist of transient receptor potential melastatin 8 (TRPM8, IC50 = 53 nM for the rat receptor).Formal Name: N-(4-fluorophenyl)-3,4-dihydro-1-[4-(trifluoromethyl)phenyl]-2(1H)-isoquinolinecarboxamide. CAS Number: 1159996-20-9. Molecular Formula: C23H18F4N2O. Formula Weight: 414.4. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMF: insol, DMSO: insol, Ethanol: 1 mg/ml, PBS (pH 7.2): insol. lambdamax: 234 nm. SMILES: O=C(N1CCC2=CC=CC=C2C1C3=CC=C(C(F)(F)F)C=C3)NC4=CC=C(C=C4)F. InChi Code: InChI=1S/C23H18F4N2O/c24-18-9-11-19(12-10-18)28-22(30)29-14-13-15-3-1-2-4-20(15)21(29)16-5-7-17(8-6-16)23(25,26)27/h1-12,21H,13-14H2,(H,28,30). InChi Key: ADCDUDFEGFKKQH-UHFFFAOYSA-N.