TC HSD 21

TC HSD 21 is an inhibitor of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3, IC50 = 14 nM in HeLa cells expressing the recombinant human enzyme). It is selective for 17beta-HSD3 over 17beta-HSD1, 17beta-HSD2, estrogen receptor alpha (ERalpha), the androgen receptor, and the glucocorticoid receptor.Formal Name: 5-[(3-bromo-4-hydroxyphenyl)methylene]-3-(4-methoxyphenyl)-2-thioxo-4-thiazolidinone. CAS Number: 330203-01-5. Synonyms: TC Hydroxysteroid Dehydrogenase 21. Molecular Formula: C17H12BrNO3S2. Formula Weight: 422.3. Purity: >98%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 100 mM. SMILES: OC1=CC=C(/C=C2SC(N(C3=CC=C(OC)C=C3)C\2=O)=S)C=C1Br. InChi Code: InChI=1S/C17H12BrNO3S2/c1-22-12-5-3-11(4-6-12)19-16(21)15(24-17(19)23)9-10-2-7-14(20)13(18)8-10/h2-9,20H,1H3/b15-9-. InChi Key: HEFKAUYVLSGPGC-DHDCSXOGSA-N.