18 products were found matching "K10207"!

Description: TC HSD 21 is a potent and highly selective inhibitor of 17beta-hydroxysteroid dehydrogenase type 3 (IC50 = 14 nM). Target: Dehydrogenase. Smiles: COc1ccc(cc1)N1C(=S)S\C(=C/c2ccc(O)c(Br)c2)C1=O. References: Harada K,et al. Identification of oxazolidinediones and thiazolidinediones as potent...

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: 17-beta-hydroxysteroid dehydrogenase type 3 Protein function: Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH. [The UniProt...

TC HSD 21 is an inhibitor of 17beta-hydroxysteroid dehydrogenase type 3 (17beta-HSD3, IC50 = 14 nM in HeLa cells expressing the recombinant human enzyme). It is selective for 17beta-HSD3 over 17beta-HSD1, 17beta-HSD2, estrogen receptor alpha (ERalpha), the androgen receptor, and the glucocorticoid receptor.Formal...

Protein function: Favors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH (PubMed:26545797, PubMed:8075637, PubMed:16216911). Androgens such as epiandrosterone, dehydroepiandrosterone, androsterone and androstanedione are accepted as substrates and reduced at...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. 17beta-Hydroxysteroid dehydrogenase 3 (17b-HSD3) is an enzyme that in humans is encoded by the HSD17B3 gene and is involved in androgen steroidogenesis. This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes...

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HSD17b3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HSD17b3....

Length: 933 Sequence: atgggggacg tcctggaaca gttcttcatc ctcacagggc tgctggtgtg cctggcctgc ctggcgaagt gcgtgagatt ctccagatgt gttttactga actactggaa agttttgcca aagtctttct tgcggtcaat gggacagtgg gcagtgatca ctggagcagg cgatggaatt gggaaagcgt actcgttcga gctagcaaaa cgtggactca atgttgtcct tattagccgg acgctggaaa aactagaggc...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia. Applications: Suitable for use in Western...