Talarozole

Item number	Size	Delivery time	Price
TGM-T7370-1mg	1 mg	7 - 10 business days*	62.00€
TGM-T7370-1mL	1 ml	7 - 10 business days*	106.00€
TGM-T7370-5mg	5 mg	7 - 10 business days*	129.00€
TGM-T7370-10mg	10 mg	7 - 10 business days*	167.00€
TGM-T7370-25mg	25 mg	7 - 10 business days*	235.00€
TGM-T7370-50mg	50 mg	7 - 10 business days*	303.00€
TGM-T7370-100mg	100 mg	7 - 10 business days*	461.00€

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Description: Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking... more

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Product information "Talarozole"

Description: Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) that inhibits CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively, for treating acne, psoriasis, and other keratinization disorders. Target: Others, Autophagy, Retinoid Receptor, P450. Smiles: CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1. References: Elizabeth Pavez Loriè, Chamcheu J C , Vahlquist A , et al. Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis[J]. Archives of Dermatological Research, 2009, 301(7):475-485.

Keywords:	R115866
Supplier:	TargetMol
Supplier-Nr:	T7370

Properties

Application:	Antiacne, Antipsoriatic
MW:	377.51 D
Formula:	C21H23N5S

Database Information

CAS :

201410-53-9| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+20°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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