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Talarozole
Item number: Cay42372-10
A CYP26 inhibitor (IC50 = 0.004 µM), selective for CYP26 over CYP2A1, CYP2C11, CYP17, and CYP19 (IC50s = 9.1, 7.2, 2.6, and 1.3 µM, respectively), increases the levels of all-trans retinoic acid in plasma, skin, liver, fat, kidneys, and spleen in rats at 2.5 mg/kg, inhibits estrogen-induced vaginal keratinization in...
| Keywords: | R115866, Rambazole, N-[4-[2-ethyl-1-(1H-1,2,4-triazol-1-yl)butyl]phenyl]-2-benzothiazolamine |
| Application: | CYP26 inhibitor |
| CAS | 201410-53-9 |
| MW: | 377.51 D |
From 142.00€
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Talarozole
Item number: TGM-T7370-100mg
Description: Talarozole (R115866) is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA) that inhibits CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM, respectively, for treating acne, psoriasis, and other keratinization disorders. Target: Others, Autophagy, Retinoid Receptor, P450....
| Keywords: | R115866 |
| Application: | Antiacne, Antipsoriatic |
| CAS | 201410-53-9 |
| MW: | 377.51 D |
From 62.00€
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