SYN1143

Item number	Size	Delivery time	Price
TGM-T8409-1mg	1 mg	7 - 10 business days*	37.00€
TGM-T8409-5mg	5 mg	7 - 10 business days*	48.00€
TGM-T8409-1mL	1 ml	7 - 10 business days*	60.00€
TGM-T8409-10mg	10 mg	7 - 10 business days*	74.00€
TGM-T8409-25mg	25 mg	7 - 10 business days*	119.00€
TGM-T8409-50mg	50 mg	7 - 10 business days*	176.00€
TGM-T8409-100mg	100 mg	7 - 10 business days*	439.00€

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Description: SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays... more

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Product information "SYN1143"

Description: SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively. Target: c-Met/HGFR. Smiles: COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1. References: Zhang Y, et, al. Identification of a novel recepteur d'origine nantais/c-met small-molecule kinase inhibitor with antitumor activity in vivo. Cancer Res. 2008 Aug 15,68(16):6680-7.

Keywords:	AMG-1, RON-IN-1
Supplier:	TargetMol
Supplier-Nr:	T8409

Properties

Application:	C-Met / Ron inhibitor
MW:	556.58 D
Formula:	C31H29FN4O5

Database Information

CAS :	913376-84-8\| Matching products
KEGG ID :	K05099 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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