3 products were found matching "913376-84-8"!
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SYN1143
Item number: TGM-T8409-100mg
Description: SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol/L, respectively. Target: c-Met/HGFR. Smiles: COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)cc3F)ccnc2c1....
| Keywords: | AMG-1, RON-IN-1 |
| Application: | C-Met / Ron inhibitor |
| CAS | 913376-84-8 |
| MW: | 556.58 D |
From 37.00€
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AMG 1
Item number: Cay41226-10
AMG 1 is an inhibitor of c-Met and Ron (IC50s = 4 and 9 nM, respectively). It is selective for c-Met and Ron over seven tyrosine and serine/threonine kinases (IC50s = 160 to 1,900 nM). AMG 1 decreases the levels of phosphorylated MET, ERK1/2, and Akt in HT-29 colon and BxPC-3 pancreatic cancer cells, as well as...
| Keywords: | KIN001-237, KIN237, RON Inhibitor 1, RON-IN-1, SYN1143,... |
| Application: | C-Met / Ron inhibitor |
| CAS | 913376-84-8 |
| MW: | 556.6 D |
From 150.00€
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AMG-1
Item number: SYN-1143-M001
Soluble in DMSO. AMG-1 is a potent inhibitor of human c-Met and RON with IC(50) values of 4 and 9nM respectively. Target: c-Met - RON , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | AMG1 |
| Application: | c-Met / RON inhibitor |
| CAS | 913376-84-8 |
| MW: | 556,6 D |
From 254.00€
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