Sunitinib . malate
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor... more
Product information "Sunitinib . malate"
Potent ATP-competitive and cell permeable multi-targeted receptor tyrosine kinase (RTK) inhibitor targeting VEGFR and PDGFR-beta. Inhibits FLK1 (Ki=9nM), PDGFRbeta (Ki=8nM) and FLT3. It is at least 10-fold selective for FLK1 and PDGFRbeta over a variety of tyrosine kinases in a panel, including EGFR, Cdk2, Met, IGFR-1, Abl and Src. Inhibits the cellular receptor phosphorylation of FLT3, RET and CSF-1R. Also shown to inhibit c-Kit. Exhibits potent antiangiogenic and antitumor activity in multiple xenograft models.
| Keywords: | SU-11248 |
| Supplier: | AdipoGen Life Sciences |
| Supplier-Nr: | AG-CR1-3707 |
Properties
| Application: | Potent cell permeable multi-targeted receptor tyrosine kinase (VEGFR, PDGFR-beta) inhibitor |
| MW: | 532.6 D |
| Formula: | C22H27FN4O2 . C4H6O5 |
| Purity: | >98% |
| Format: | Liquid |
Database Information
| CAS : | 341031-54-7| Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
| GHS Hazard Pictograms: |
|
| H Phrases: | H360, H372 |
| P Phrases: | P201, P308+P313 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed