STING18

STING18
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay28319-1 1 mg -

6 - 10 business days*

132.00€
Cay28319-5 5 mg -

6 - 10 business days*

581.00€
 
STING18 is a competitive ligand of stimulator of interferon genes (STING, IC50 = 0.068 µM in a... more
Product information "STING18"
STING18 is a competitive ligand of stimulator of interferon genes (STING, IC50 = 0.068 µM in a radioligand binding assay). It inhibits cGAMP-induced IFN-beta production (IC50 = 11 µM) but does not stimulate IFN-beta production (EC50 = >30 µM) in THP-1 cells.Formal Name: 2-[3-chloro-4-(1,1-dimethylethyl)phenyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-7-fluoro-1,2,3,4-tetrahydro-1-oxo-4-isoquinolineacetic acid. CAS Number: 2706536-26-5. Synonyms: Stimulator of Interferon Genes 18. Molecular Formula: C29H27ClFNO5. Formula Weight: 524.0. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMF:PBS (pH 7.2) (1:8): 0.11 mg/ml, DMSO: 5 mg/ml. SMILES: FC1=CC=C2C(C(N(C3=CC(Cl)=C(C(C)(C)C)C=C3)C(C4=CC(OCCO5)=C5C=C4)C2CC(O)=O)=O)=C1. InChi Code: InChI=1S/C29H27ClFNO5/c1-29(2,3)22-8-6-18(14-23(22)30)32-27(16-4-9-24-25(12-16)37-11-10-36-24)20(15-26(33)34)19-7-5-17(31)13-21(19)28(32)35/h4-9,12-14,20,27H,10-11,15H2,1-3H3,(H,33,34). InChi Key: JAIAHSWXASHNQH-UHFFFAOYSA-N.
Keywords: 2-(2-(4-(tert-butyl)-3-chlorophenyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-7-fluoro-1-oxo-1,2,3,4-tetrahydroisoquinolin-4-yl)acetic acid
Supplier: Cayman Chemical
Supplier-Nr: 28319

Properties

Application: ERIS competitive ligand
MW: 524 D
Formula: C29H27ClFNO5
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 2706536-26-5| Matching products
KEGG ID : K12654 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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