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Description: SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 µM) and exhibits more than 230-fold lower potency for SIRT2 and SIRT3. Target: Sirtuin, Autophagy. Smiles: O=C(NC1=C(C=CC=C1)C1=CN2C(CN3CCNCC3)=CSC2=N1)C1=CN=C2C=CC=CC2=N1. References: Yu L, et al. Protective effects of SRT1720 via the HNF1alpha/FXR signalling pathway and anti-inflammatory mechanisms in mice with estrogen-induced cholestatic liver injury. Toxicol Lett. 2016 Dec 15,264:1-11.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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