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SRT 1720
Item number: Cay42531-10
A SIRT1 activator (EC1.5 = 0.16 µM in a cell-free fluorescence polarization assay), reduces acetylated p53 levels in U2OS cells at 0.1 µM, reduces fed blood glucose levels, improves insulin sensitivity, and increases mitochondrial capacity in a DIO mouse model of diabetes at 100 mg/kg, improves liver, adipose...
| Keywords: | CAY10559, SIRT 1933, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-quinoxalinecarboxamide |
| Application: | SIRT1 activator |
| CAS | 925434-55-5 |
| MW: | 469.56 D |
From 82.00€
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SRT 1720
Item number: TGM-T5096-5mg
Description: SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 µM) and exhibits more than 230-fold lower potency for SIRT2 and SIRT3. Target: Sirtuin, Autophagy. Smiles: O=C(NC1=C(C=CC=C1)C1=CN2C(CN3CCNCC3)=CSC2=N1)C1=CN=C2C=CC=CC2=N1. References: Yu L, et al. Protective effects of SRT1720 via the...
| CAS | 925434-55-5 |
| MW: | 469.56 D |
From 30.00€
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