SPP 86
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
A RET inhibitor (IC50 = 0.008 µM), selective for RET over a panel of 44 serine/threonine/tyrosine... more
Product information "SPP 86"
A RET inhibitor (IC50 = 0.008 µM), selective for RET over a panel of 44 serine/threonine/tyrosine kinases at 10 µM but does inhibit nine by >75%, selective for RET over a panel of 63 receptor and non-receptor tyrosine kinases 0.4 µM but does inhibit six, including RET, by >75%, reduces the proliferation of HCT116 and TPC-1 cells (EC50s = 2.4 and 3.3 µM, respectively), inhibits viral replication in FMDV-infected BHK-21 cells at 5 µM
| Keywords: | 1-(1-methylethyl)-3-(2-phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 37390 |
Properties
| Application: | RET inhibitor |
| MW: | 277.32 D |
| Formula: | C16H15N5 |
| Purity: | >98% |
| Format: | Solid |
Database Information
| CAS : | 1357349-91-7| Matching products |
| KEGG ID : | K05126 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Warning |
| GHS Hazard Pictograms: |
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| H Phrases: | (none), H302 |
| P Phrases: | P264, P270, P301+310, P330, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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