SKF 97541
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You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SKF 97541 is a GABAB receptor agonist. It reduces forskolin-induced cAMP accumulation in rat... more
Product information "SKF 97541"
SKF 97541 is a GABAB receptor agonist. It reduces forskolin-induced cAMP accumulation in rat cortical slices when used at concentrations of 30 and 100 µM. SKF 97541 reduces excitatory postsynaptic potentials (EPSPs) induced by bicuculline (Cay11727) in rat striatal slices (EC50 = 0.092 µM), an effect that can be blocked by CGP 35348 (Cay18599). It also hyperpolarizes neurons in the substantia nigra in rat brain slices (EC50 = 0.15 µM). SKF 19541 (0.01 and 0.05 mg/kg) reduces the time spent immobile in the forced swim test in rats without reducing basal locomotor activity. SMILES O=P(C)(CCCN)O InChi Code InChI=1S/C4H12NO2P/c1-8(6,7)4-2-3-5/h2-5H2,1H3,(H,6,7) InChi Key NHVRIDDXGZPJTJ-UHFFFAOYSA-N
| Keywords: | CGP 35024, P-(3-aminopropyl)-P-methyl-phosphinic acid |
| Supplier: | Cayman Chemical |
| Supplier-Nr: | 43784 |
Properties
| Application: | GABA-B receptor agonist |
| MW: | 137.12 D |
| Formula: | C4H12NO2P |
| Purity: | >98% |
| Format: | Crystalline Solid |
Database Information
| CAS : | 127729-35-5| Matching products |
| KEGG ID : | K04615 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: -20°C) |
| Signal Word: | Danger |
| GHS Hazard Pictograms: |
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| H Phrases: | H301, H319 |
| P Phrases: | P264, P270, P280, P301+310, P305+351+338, P321, P330, P337+313, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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