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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| TGM-T41260-2mg | 2 mg |
7 - 10 business days* |
54.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Description: SC144 hydrochloride, a first-in-class, orally active, small-molecule gp130... more
Product information "SC144 hydrochloride"
Description: SC144 hydrochloride, a first-in-class, orally active, small-molecule gp130 (IL6-beta) inhibitor, demonstrates potent inhibition of gp130 ligand-triggered signaling. By binding to gp130, it initiates gp130 phosphorylation (S782) and deglycosylation, impedes Stat3 phosphorylation and nuclear translocation, and suppresses the expression of downstream target genes. Furthermore, SC144 hydrochloride effectively induces apoptosis in human ovarian cancer cells [1]. Target: Others. Smiles: Cl.O=C(NNC1=NC=2C=C(F)C=CC2N3C=CC=C13)C4=NC=CN=C4
| Supplier: | TargetMol |
| Supplier-Nr: | T41260 |
Properties
| Application: | gp130 inhibitor |
| MW: | 358.76 D |
| Formula: | C16H12ClFN6O |
Database Information
| CAS : | 917497-70-2| Matching products |
| KEGG ID : | K05060 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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