107 products were found matching "K05060"!
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Anti-gp130 (Capture/Detector)
Item number: E-AN004650P.1
TISSUE SPECIFICITY: Expression not restricted to IL6-responsive cells. Found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver. Found in all the cell lines tested except BaF-B03. Expressed paraventricular nucleus of the hypothalamus (PubMed:28402851). {ECO:0000269, PubMed:1602143, ECO:0000269,...
| Keywords: | Anti-CD130, Anti-gp130, Anti-IL-6RB, Anti-IL-6R-beta, Anti-IL-6R subunit beta, Anti-Membrane glycoprotein 130, Anti-IL-6... |
| Application: | ELISA Capture/Detector |
| Host: | Rabbit |
| Species reactivity: | human,mouse,rat |
From 158.00€
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IL6ST Protein (Fc Tag) (recombinant human)
Item number: E-PDMH100221.100
Sequence: Glu23-Glu619. Fusion tag: C-Fc Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 90-100 kDa. Protein function: Protein function: Signal-transducing molecule (PubMed:2261637). The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize...
| Keywords: | gp130, CD130, CDw130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
| Expressed in: | Mammalian |
| Origin: | human |
From 304.00€
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IL6ST Protein (His Tag) (recombinant human)
Item number: E-PDMH100237.100
Sequence: Glu23-Glu619. Fusion tag: C-His Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 80-100 kDa. Protein function: Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all...
| Keywords: | gp130, CD130, CDw130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta,... |
| Expressed in: | Mammalian |
| Origin: | human |
From 304.00€
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gp130 Protein (His Tag) (recombinant mouse)
Item number: E-PDMM100086.100
Sequence: Met1-Glu617. Fusion tag: C-His Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method Observed Molecular Mass: 80-90 kDa. Protein function: Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta, or CD130) is a transmembrane protein that is the founding member of the class of all...
| Keywords: | gp130, CD130, IL-6RB, IL-6R-beta, IL-6R subunit beta, Membrane glycoprotein 130, IL-6 receptor subunit beta, Interleukin-6... |
| Expressed in: | Mammalian |
| Origin: | mouse |
From 304.00€
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LMT-28
Item number: TGM-T15769-100mg
Description: LMT-28 is an inhibitor of IL-6 and selectively inhibits IL-6-induced phosphorylation of gp130, STAT3, and JAK2. Target: IL Receptor. Smiles: CCCCCC(=C)[C@@H](O)[C@H](C)C(=O)N1[C@H](COC1=O)C(C)C. References: Hong SS, et al. A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor beta Subunit,...
| Application: | gp130 (CD130)-IL6/IL6Ralpha protein-protein interaction inhibitor |
| CAS | 1239600-18-0 |
| MW: | 311.42 D |
From 31.00€
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SC144 hydrochloride
Item number: TGM-T41260-2mg
Description: SC144 hydrochloride, a first-in-class, orally active, small-molecule gp130 (IL6-beta) inhibitor, demonstrates potent inhibition of gp130 ligand-triggered signaling. By binding to gp130, it initiates gp130 phosphorylation (S782) and deglycosylation, impedes Stat3 phosphorylation and nuclear...
| Application: | gp130 inhibitor |
| CAS | 917497-70-2 |
| MW: | 358.76 D |
54.00€
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RCGD423
Item number: TGM-T5359-100mg
Description: RCGD423, a small molecule gp130 modulator, prevents articular cartilage degeneration and promotes repair. Target: Interleukin. Smiles: Brc1ccc(Nc2nc(cs2)-c2ccccc2)cc1. References: Shkhyan R, et al. Drug-induced modulation of gp130 signalling prevents articular cartilage degeneration and promotes repair....
| Application: | gp130 modulator |
| CAS | 108237-91-8 |
| MW: | 331.23 D |
From 31.00€
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gp130/IL6ST Protein, Human, Recombinant (His & hFc)
Item number: TGM-TMPY-01076-100ug
Description: gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
| Keywords: | GP130, interleukin 6 signal transducer, IL-6RB, CD130, CDW130 |
| MW: | 96 kD |
From 190.00€
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gp130/IL6ST Protein, Human, Recombinant (His)
Item number: TGM-TMPK-00412-100ug
Description: gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities...
| Keywords: | IL-6R-beta, gp130, CD130, IL6ST, IL-6 R beta, CDw130, IL-6R-beta, IL-6RB, gp130/CD130/IL-6 R beta, IL-6 R beta |
| MW: | 68.94 kD |
From 369.00€
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gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK)
Item number: TGM-TMPY-06039-100ug
Description: gp130/IL6ST Protein, Human, Recombinant (aa 1-618, DDDDK) is expressed in HEK293 mammalian cells. The predicted molecular weight is 68.4 kDa and the accession number is P40189-1.
| Keywords: | IL-6RB, CDW130, interleukin 6 signal transducer, CD130, GP130 |
| MW: | 68.4 kD |
From 699.00€
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gp130/IL6ST Protein, Rat, Recombinant (His)
Item number: TGM-TMPY-02148-100ug
Description: gp130/IL6ST Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68.2 kDa and the accession number is H9BFG4.
| Keywords: | interleukin 6 signal transducer |
| MW: | 68.2 kD |
699.00€
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gp130/IL6ST Protein, Rat, Recombinant (His & mFc)
Item number: TGM-TMPY-01995-100ug
Description: gp130/IL6ST Protein, Rat, Recombinant (His & mFc) is expressed in HEK293 mammalian cells with His, mFc tag. The predicted molecular weight is 94.3 kDa and the accession number is H9BFG4.
| Keywords: | interleukin 6 signal transducer |
| MW: | 94.3 kD |
699.00€
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