sbp-7455

Item number	Size	Delivery time	Price
TGM-T8850-1mg	1 mg	7 - 10 business days*	60.00€
TGM-T8850-5mg	5 mg	7 - 10 business days*	119.00€
TGM-T8850-10mg	10 mg	7 - 10 business days*	201.00€
TGM-T8850-25mg	25 mg	7 - 10 business days*	362.00€
TGM-T8850-50mg	50 mg	7 - 10 business days*	592.00€
TGM-T8850-100mg	100 mg	7 - 10 business days*	743.00€

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Description: SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced... more

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Product information "sbp-7455"

Description: SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice. Target: Autophagy. Smiles: COc1ccc(Nc2ncc(c(NC3CC3)n2)C(F)(F)F)cc1OC. References: Ren H, Bakas NA, Vamos M, et al. Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2020,63(23):14609-14625. doi:10.1021/acs.jmedchem.0c00873

Supplier:	TargetMol
Supplier-Nr:	T8850

Properties

Application:	ULK1 / ULK2 dual inhibitor
MW:	354.33 D
Formula:	C16H17F3N4O2

Database Information

CAS :	1884222-74-5\| Matching products
KEGG ID :	K08269 \| Matching products

Handling & Safety

Storage:	-20°C
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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